Diarrhea and other lower intestinal fluid losses will contribute to:
Increase in HCO3-
Decrease in HCO3-
Increase the chance of Alkalosis
Has no effect on pH of blood
The Correct Answer is B
Choice A Reason:
An increase in HCO3- (bicarbonate) is not typically associated with diarrhea and lower intestinal fluid losses. In fact, the opposite is true. Diarrhea often leads to a loss of bicarbonate, which can result in metabolic acidosis. Therefore, this choice is incorrect.
Choice B Reason:
This is the correct answer. Diarrhea and other lower intestinal fluid losses lead to a decrease in HCO3- levels. The loss of bicarbonate from the body results in a lower pH, contributing to metabolic acidosis. This condition occurs because bicarbonate is a key buffer that helps maintain the acid-base balance in the blood.
Choice C Reason:
An increase in the chance of alkalosis is not typically associated with diarrhea. Alkalosis refers to a condition where the pH of the blood is higher than normal, which can occur due to a loss of hydrogen ions or an increase in bicarbonate. However, diarrhea usually causes a loss of bicarbonate, leading to acidosis rather than alkalosis.
Choice D Reason:
Saying that diarrhea has no effect on the pH of the blood is incorrect. Diarrhea can significantly impact the acid-base balance in the body by causing a loss of bicarbonate, leading to metabolic acidosis. Therefore, this choice is incorrect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A: Beta 2 Agonist Decreases Blood Pressure
Beta 2 agonists primarily cause bronchodilation and vasodilation, which can lead to a decrease in blood pressure. However, this is not their primary function, and they are more commonly associated with the relaxation of smooth muscles in the airways.
Choice B: Beta 1 Agonist Increases Blood Pressure
Beta 1 receptors are primarily located in the heart. Activation of these receptors increases heart rate and contractility, which in turn increases cardiac output and blood pressure. Therefore, beta 1 agonists are known to increase blood pressure.
Choice C: Beta 2 Agonist Reduces Blood Pressure
Similar to choice A, beta 2 agonists can cause vasodilation, which may reduce blood pressure. However, this is not their primary therapeutic use, and they are mainly used for their bronchodilatory effects.
Choice D: Beta 1 Agonist Reduces Blood Pressure
Beta 1 agonists increase heart rate and contractility, leading to an increase in blood pressure. Therefore, this statement is incorrect as beta 1 agonists do not reduce blood pressure.
Correct Answer is A
Explanation
Choice A: Alpha 1 Agonist and Alpha 2 Antagonist Increase Blood Pressure
Alpha 1 receptors are primarily located on the smooth muscles of blood vessels. When activated by an agonist, these receptors cause vasoconstriction, which increases blood pressure. On the other hand, alpha 2 receptors are found on presynaptic nerve terminals and act to inhibit the release of norepinephrine. An antagonist at alpha 2 receptors would prevent this inhibition, leading to increased norepinephrine release, further promoting vasoconstriction and increasing blood pressure. Therefore, the combination of an alpha 1 agonist and an alpha 2 antagonist would synergistically increase blood pressure.
Choice B: Alpha 1 Agonist and Alpha 2 Agonist Decrease Blood Pressure
Alpha 1 agonists increase blood pressure by causing vasoconstriction. Alpha 2 agonists, however, decrease blood pressure by inhibiting norepinephrine release, leading to vasodilation. Therefore, this combination would not decrease blood pressure as the effects of the alpha 1 agonist would counteract the effects of the alpha 2 agonist.
Choice C: Alpha 1 and Alpha 2 Agonist Increase Blood Pressure
While alpha 1 agonists increase blood pressure through vasoconstriction, alpha 2 agonists actually decrease blood pressure by reducing norepinephrine release. Therefore, this statement is incorrect as the combined effect would not result in an increase in blood pressure.
Choice D: Alpha 1 Antagonist and Alpha 2 Agonist Decrease Blood Pressure
Alpha 1 antagonists block the vasoconstrictive action of alpha 1 receptors, leading to vasodilation and a decrease in blood pressure. Alpha 2 agonists also decrease blood pressure by inhibiting norepinephrine release. Therefore, this combination would indeed decrease blood pressure, making this statement partially correct but not the best answer compared to choice A.
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