A nurse is explaining the pathophysiology of lymphoma to a group of nursing students.
What key process occurs in the development of lymphoma?
Lymphocytes undergo apoptosis and eliminate the tumor cells.
Altered lymphocytes proliferate and form a tumor mass.
The tumor mass inhibits angiogenesis.
The tumor cells are unable to spread beyond the lymphatic system.
The Correct Answer is B
Choice A rationale:
Lymphoma is characterized by the abnormal proliferation of lymphocytes, not their apoptosis.
In lymphoma, lymphocytes become altered and undergo uncontrolled growth, leading to the formation of a tumor mass.
Choice B rationale:
This is the correct answer.
In lymphoma, altered lymphocytes proliferate and form a tumor mass.
This abnormal proliferation of lymphocytes is a key process in the development of lymphoma.
Choice C rationale:
The tumor mass in lymphoma does not inhibit angiogenesis.
In fact, it may induce angiogenesis to supply nutrients to the growing tumor.
Angiogenesis is the process of forming new blood vessels, and it is often seen in tumors to ensure their blood supply.
Choice D rationale:
Lymphoma tumor cells can spread beyond the lymphatic system to other parts of the body.
This spread is a significant concern in lymphoma, as it can lead to metastasis.
Therefore, this statement is not accurate.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale:
Fever exceeding 38°C is a common symptom in HL, known as "Pel-Ebstein fever." This cyclic pattern of fever is characteristic of Hodgkin's lymphoma, but it is not the only common symptom.
Therefore, this choice is partially correct but not the most comprehensive.
Choice B rationale:
Significant unexplained weight loss over a period of six months or less is a classic "B" symptom associated with HL.
B symptoms are systemic symptoms that indicate a more advanced stage of the disease and typically include fever, night sweats, and weight loss exceeding 10% of the patient's baseline.
This choice is correct and represents a hallmark of HL.
Choice C rationale:
Abdominal pain and fullness are not typically associated with Hodgkin's lymphoma.
These symptoms are more commonly linked to other lymphoproliferative disorders or non-Hodgkin's lymphoma (NHL)
Choice D rationale:
Difficulty breathing is not a primary symptom of Hodgkin's lymphoma.
While it is possible for HL to cause enlarged lymph nodes in the mediastinum, leading to compression of the airways, this is not a common presenting symptom.
Correct Answer is ["A","B","D"]
Explanation
Choice A rationale:
Enlarged lymph nodes are a common clinical manifestation of lymphoma.
Lymphoma can cause the lymph nodes to become enlarged and painless.
Choice B rationale:
Unexplained weight loss is a common systemic symptom of lymphoma.
It is often one of the "B symptoms" used to classify the stage of lymphoma.
Choice C rationale:
Elevated blood sugar levels are not typically associated with lymphoma.
This is not a common clinical manifestation of the disease.
Choice D rationale:
Night sweats are another common systemic symptom of lymphoma.
They are also considered one of the "B symptoms" that may be present in patients with lymphoma.
Choice E rationale:
Increased blood pressure is not a typical clinical manifestation of lymphoma.
It is not directly related to the disease process.
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