Order: 1 liter or 1000 mL of D5W to infuse over 6 hours

Available: Macrodrip set: 10 gtt/mL

The IV flow rate would be ______gtt/min.

A) Anticoagulants:
Anticoagulants, such as warfarin, heparin, and direct oral anticoagulants (DOACs), are specifically designed to prevent the formation of blood clots or to treat existing clots. They work by interfering with various stages of the clotting cascade, either by inhibiting clotting factors or by enhancing the effects of natural anticoagulants in the body.

B) Antihypertensives:
Antihypertensives, such as ACE inhibitors, beta blockers, and calcium channel blockers, are used to lower high blood pressure by relaxing blood vessels, reducing heart rate, or decreasing fluid retention. While antihypertensives can reduce the overall strain on the heart and blood vessels, they do not have an impact on the clotting process and are not designed to interfere with blood coagulation.

C) Antibiotics:
Antibiotics, such as penicillin or amoxicillin, target bacteria and prevent their growth or kill them, but they do not affect the clotting mechanisms in the blood.

D) Antipyretics:
Antipyretics, such as acetaminophen (Tylenol) or ibuprofen, work by lowering the body's set point temperature in the hypothalamus, helping to relieve fever. They do not affect the clotting cascade or the ability of blood to form clots, so antipyretics are a correct answer.

E) Antiemetics:
Antiemetics, such as ondansetron or metoclopramide, are used to prevent or treat nausea and vomiting. They primarily work by blocking the receptors in the brain that trigger nausea and vomiting but do not have an effect on the clotting process. Thus, antiemetics are a correct answer.

Given:

Ordered dose of Heparin: 18 units/kg/hr

Patient weight: 123 pounds

Concentration of Heparin: 25,000 units/250 mL (100 units/mL)

Step 1: Convert patient weight from pounds to kilograms:

1 pound (lb) = 0.453592 kilograms (kg)

Patient weight in kg = 123 lbs x 0.453592 kg/lb = 55.7923 kg

Step 2: Calculate the total dose of Heparin in units/hr:

Total dose (units/hr) = Ordered dose (units/kg/hr) x Patient weight (kg)

Total dose (units/hr) = 18 units/kg/hr x 55.7923 kg

Total dose (units/hr) = 1004.2614 units/hr

Step 3: Calculate the infusion rate in mL/hr:

Infusion rate (mL/hr) = Total dose (units/hr) / Concentration (units/mL)

Infusion rate (mL/hr) = 1004.2614 units/hr / 100 units/mL

Infusion rate (mL/hr) = 10.042614 mL/hr

Step 4: Round to the nearest tenths:

Infusion rate (mL/hr) ≈ 10.0 mL/hr