Order: dobutamine 5 mcg/kg/min
Patient's weight: 152 lb
Available: dobutamine 500 mg in 250 mL D5W
What is the flow rate in ml/hr? (Round to the nearest tenths)
9 mL/hr
103.5 mL/hr
11 mu/hr
10.4 mL/hr
The Correct Answer is D
1. Convert patient weight from pounds to kilograms:
Patient weight (kg) = 152 lb x 0.453592 kg/lb = 68.94 kg
2. Calculate the desired dose in mcg/min:
Desired dose (mcg/min) = 5 mcg/kg/min x 68.94 kg = 344.7 mcg/min
3. Convert mcg/min to mg/min:
Desired dose (mg/min) = 344.7 mcg/min / 1000 mcg/mg = 0.3447 mg/min
4. Calculate the concentration of dobutamine in the solution:
Concentration (mg/mL) = 500 mg / 250 mL = 2 mg/mL
5. Calculate the flow rate in mL/min:
Flow rate (mL/min) = Desired dose (mg/min) / Concentration (mg/mL)
Flow rate (mL/min) = 0.3447 mg/min / 2 mg/mL = 0.17235 mL/min
6. Calculate the flow rate in mL/hr:
Flow rate (mL/hr) = 0.17235 mL/min x 60 min/hr = 10.341 mL/hr
7. Round to the nearest tenth:
Flow rate (mL/hr) = 10.3 mL/hr
Therefore, the correct answer is 10.4 mL/hr
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
A) Transdermal patch:
Transdermal patches are designed for slow, continuous delivery of medication through the skin over a long period of time, typically 24 hours. Although they provide steady medication levels, they do not offer a rapid onset of action. This route is more suitable for long-term control of conditions like angina but is not the fastest for immediate relief.
B) Topical ointment:
Topical ointments are applied to the skin and absorb slowly. While they may have local effects, they are not used for quick systemic effects. In the case of nitroglycerin, topical ointments are generally used for sustained release over several hours and are not intended for immediate relief of chest pain.
C) Suspended release:
Suspended release formulations are designed to release the drug slowly over time. Like transdermal patches, these formulations are meant for long-term management, not for rapid onset. A suspended release formulation of nitroglycerin would not provide the immediate relief that is typically needed in cases of acute angina or chest pain.
D) Sublingual:
The sublingual route provides the most rapid onset of action for nitroglycerin. When nitroglycerin is placed under the tongue, it is absorbed directly into the bloodstream through the mucous membranes of the mouth. This bypasses the digestive system and the liver (first-pass metabolism), allowing the drug to take effect quickly—usually within 1 to 3 minutes—making it ideal for acute relief of chest pain or angina. This route is commonly used for emergencies when rapid relief is needed.
Correct Answer is A
Explanation
Given:
Ordered dose of Dopamine: 3 mcg/kg/min
Child's weight: 41.8 lbs
Concentration of Dopamine: 400 mg in 250 mL D5W
Step 1: Convert child's weight from pounds to kilograms:
1 pound (lb) = 0.453592 kilograms (kg)
Child's weight in kg = 41.8 lbs x 0.453592 kg/lb = 18.935 kg
Step 2: Calculate the total dose of Dopamine in mcg/min:
Total dose (mcg/min) = Ordered dose (mcg/kg/min) x Child's weight (kg)
Total dose (mcg/min) = 3 mcg/kg/min x 18.935 kg
Total dose (mcg/min) = 56.805 mcg/min
Step 3: Convert mcg to mg:
Total dose (mg/min) = Total dose (mcg/min) / 1000 mcg/mg
Total dose (mg/min) = 56.805 mcg/min / 1000 mcg/mg
Total dose (mg/min) = 0.056805 mg/min
Step 4: Calculate the total dose in mg/hr:
Total dose (mg/hr) = Total dose (mg/min) x 60 min/hr
Total dose (mg/hr) = 0.056805 mg/min x 60 min/hr
Total dose (mg/hr) = 3.4083 mg/hr
Step 5: Calculate the infusion rate in mL/hr:
Infusion rate (mL/hr) = Total dose (mg/hr) / Concentration (mg/mL)
Infusion rate (mL/hr) = 3.4083 mg/hr / (400 mg/250 mL)
Infusion rate (mL/hr) = 3.4083 mg/hr x (250 mL/400 mg)
Infusion rate (mL/hr) = 2.1301875 mL/hr
Step 6: Round to the nearest tenth:
Infusion rate (mL/hr) ≈ 2.1 mL/hr
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