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Order: dobutamine 5 mcg/kg/min

Patient's weight: 152 lb

Available: dobutamine 500 mg in 250 mL D5W

What is the flow rate in ml/hr? (Round to the nearest tenths)

A.

9 mL/hr

B.

103.5 mL/hr

C.

11 mu/hr

D.

10.4 mL/hr

Answer and Explanation

The Correct Answer is D

1. Convert patient weight from pounds to kilograms:

Patient weight (kg) = 152 lb x 0.453592 kg/lb = 68.94 kg

2. Calculate the desired dose in mcg/min:

Desired dose (mcg/min) = 5 mcg/kg/min x 68.94 kg = 344.7 mcg/min

3. Convert mcg/min to mg/min:

Desired dose (mg/min) = 344.7 mcg/min / 1000 mcg/mg = 0.3447 mg/min

4. Calculate the concentration of dobutamine in the solution:

Concentration (mg/mL) = 500 mg / 250 mL = 2 mg/mL

5. Calculate the flow rate in mL/min:

Flow rate (mL/min) = Desired dose (mg/min) / Concentration (mg/mL)

Flow rate (mL/min) = 0.3447 mg/min / 2 mg/mL = 0.17235 mL/min

6. Calculate the flow rate in mL/hr:

Flow rate (mL/hr) = 0.17235 mL/min x 60 min/hr = 10.341 mL/hr

7. Round to the nearest tenth:

Flow rate (mL/hr) = 10.3 mL/hr

Therefore, the correct answer is 10.4 mL/hr


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Related Questions

Correct Answer is B

Explanation

A) Esophagus
Enteric-coated tablets are designed to not dissolve or disintegrate in the esophagus. They are coated with a protective layer that prevents the tablet from breaking down in the acidic environment of the stomach. This is to ensure that the medication is released in the part of the digestive tract where it is most needed, typically beyond the stomach.

B) Duodenum
Enteric-coated tablets are designed to disintegrate in the duodenum, which is the first part of the small intestine. The coating protects the tablet from stomach acid, allowing it to pass intact through the stomach and into the small intestine, where the pH is higher and the coating dissolves, releasing the medication for absorption.

C) Stomach
Enteric-coated tablets are specifically designed not to disintegrate in the stomach because the stomach's acidic environment could either damage the drug or cause premature release. The coating ensures that the drug is protected until it reaches the more neutral pH of the duodenum.

D) Colon
The colon is too far along in the digestive tract for enteric-coated tablets to typically disintegrate. The design of enteric coatings is intended to protect the drug until it reaches the duodenum, where absorption is most efficient. Enteric coatings are not meant to disintegrate in the colon.

Correct Answer is B

Explanation

Given:

Ordered dose of Digoxin: 0.375 mg daily

Available Digoxin tablets: 0.25 mg/tablet

Step 1: Set up the proportion:

Desired dose (mg) / Available tablet strength (mg/tablet) = Number of tablets

Step 2: Substitute the values:

0.375 mg / 0.25 mg/tablet = Number of tablets

Step 3: Calculate the number of tablets:

Number of tablets = 0.375 mg ÷ 0.25 mg/tablet

Number of tablets = 1.5 tablets

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