Order: Ceftriaxone 300 mg IV Q12H for a 6 month old infant with a serious infection who weighs 18 lbs. The recommended dosage is 50-75 mg/kg/day in divided doses BID. Prove mathematically (mg/kg/day) the ordered dose and is it safe to give Safe/Unsafe)?

A.While cystic fibrosis is characterized by a high concentration of sodium chloride in sweat due to defective chloride channels, this is not the cause of the barrel chest and clubbing of the fingers.

B.The barrel chest and clubbing of the fingers are often seen in children with cystic fibrosis due to chronic hypoxia (lack of oxygen). Chronic lung infections, airway obstruction, and respiratory insufficiency associated with cystic fibrosis lead to prolonged low oxygen levels, which can result in these physical changes.

C.Decreased respiratory capacity, often due to the chronic respiratory issues associated with cystic fibrosis, can result in a barrel chest (increased chest diameter due to air trapping) and clubbing of the fingers (a sign of chronic hypoxia).

D.Decreased respiratory capacity (due to thick mucus and airway obstruction) does contribute to chronic respiratory issues in cystic fibrosis, but the direct cause of the barrel chest and clubbing is the chronic lack of oxygen (hypoxia) rather than decreased capacity alone. The changes in the chest and fingers are a result of prolonged oxygen deprivation.

A. The child has the beginning signs of tooth eruption:

Teething usually begins around 4-7 months of age, so the beginning signs of tooth eruption (teething) are typical at six months.

B. The child is able to track and follow objects:

By six months, most infants can track and follow objects with their eyes, which is a normal developmental milestone for this age.

C. The child’s anterior fontanel is open:

The anterior fontanelle, the soft spot at the top of the baby's head, remains open until around 18-24 months of age, so its presence at six months is expected and considered normal.

D. The child’s posterior fontanel is open.

By six months of age, the posterior fontanelle, the soft spot located at the back of the baby's head, typically closes or is significantly smaller than it was at birth. The posterior fontanelle usually closes between 2 to 4 months of age in most infants. If it remains noticeably open by six months, it might warrant further evaluation as it could be indicative of a developmental or medical issue.