Primary hypertension:

Is caused by hypertrophy and hyperplasia with associated fibrosis of the intima and media

Underactivity of the sympathetic nervous system and the RAAS

is caused by complicated interactions of genetics and the environment without evidence of a specific causative agent

is caused by systemic disease that raises peripheral vascular resistance and/or cardiac output

Answer and Explanation

The Correct Answer is C

A. Is caused by hypertrophy and hyperplasia with associated fibrosis of the intima and media: While these changes can occur in the vascular walls over time due to hypertension, they are not the primary cause of primary hypertension itself. Primary hypertension is more complex and multifactorial.

B. Underactivity of the sympathetic nervous system and the RAAS: Primary hypertension is characterized by increased activity of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS), not underactivity. Increased activity of these systems contributes to elevated blood pressure.

C. Is caused by complicated interactions of genetics and the environment without evidence of a specific causative agent: This statement accurately describes primary hypertension, which results from a combination of genetic predisposition and environmental factors such as diet, physical activity, and stress. There is no single identifiable cause for primary hypertension, making this the correct answer.

D. Is caused by systemic disease that raises peripheral vascular resistance and/or cardiac output: This statement pertains more to secondary hypertension, which is due to identifiable causes such as kidney disease, endocrine disorders, or other systemic diseases. Primary hypertension does not arise from a specific systemic disease but rather from multifactorial influences.

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Correct Answer is C

Explanation

A. Fungus: While fungal infections can cause infective endocarditis, they are much less common compared to bacterial infections. Fungal endocarditis typically occurs in immunocompromised individuals or those with specific risk factors.

B. Virus: Viral infections can affect the heart, but they are not a common cause of infective endocarditis. Most cases of endocarditis are associated with bacterial infections rather than viral ones.

C. Bacterium: The most common cause of infective endocarditis is bacterial infection. Bacteria, particularly Staphylococcus aureus, Streptococcus viridans, and Enterococcus, are frequently implicated in this condition. These bacteria can enter the bloodstream and adhere to heart valves or damaged cardiac tissue, leading to infection and inflammation.

D. Rickettsiae: Rickettsial infections are caused by a specific type of bacteria that are typically transmitted through arthropod vectors, such as ticks. While they can cause various illnesses, they are not a common cause of infective endocarditis.

A. Hospital-acquired pneumonia B. Immunocompromised pneumonia C. Community-acquired pneumonia D. Viral pneumonia

Correct Answer is A

Explanation

A. Hospital-acquired pneumonia: Pneumonia that develops 48 hours or more after hospital admission is classified as hospital-acquired pneumonia (HAP). It is caused by pathogens acquired in the hospital setting, often involving multidrug-resistant organisms such as Pseudomonas aeruginosa, Staphylococcus aureus (including MRSA), and Klebsiella pneumoniae. Patients who are intubated, have prolonged hospital stays, or have weakened immune defenses are at higher risk.

B. Immunocompromised pneumonia: Pneumonia in immunocompromised patients occurs due to weakened host defenses, such as in individuals with HIV/AIDS, those undergoing chemotherapy, or transplant recipients on immunosuppressive therapy. While these patients can develop HAP, pneumonia due to opportunistic infections like Pneumocystis jirovecii or fungal infections is categorized separately.

C. Community-acquired pneumonia: Pneumonia acquired outside the hospital or within the first 48 hours of admission is classified as community-acquired pneumonia (CAP). Typical pathogens include Streptococcus pneumoniae, Haemophilus influenzae, and Mycoplasma pneumoniae. CAP is usually less resistant to antibiotics compared to HAP.

D. Viral pneumonia: Pneumonia caused by viral pathogens such as influenza, respiratory syncytial virus (RSV), or SARS-CoV-2 is classified based on the causative agent rather than the setting in which it was acquired. Although viruses can cause both CAP and HAP, the classification of pneumonia is determined by the timing of onset and exposure risks.

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Primary hypertension:

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Naxlex Comprehensive Predictor Exams

What is the common cause of infective carditis?

Correct Answer is C

Explanation

A pneumonia that occurs 48 hours or more after admission to the hospital is considered:

Correct Answer is A

Explanation

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