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release secretions into the duodenum of the small intestine.

A. Gallbladder: The gallbladder stores and releases bile into the duodenum via the common bile duct when stimulated (e.g., by CCK). It does release a secretion into the duodenum, but it primarily stores bile produced by the liver.
B. Liver: The liver produces bile, which drains via hepatic ducts into the common bile duct and empties into the duodenum -the liver is a primary secretor whose products reach the duodenum.
C. Spleen: The spleen is a lymphoid/hematologic organ (filters blood, immune functions) and does not release digestive secretions into the duodenum.
D. Gastric glands: Gastric glands secrete gastric juice into the stomach lumen (not the duodenum), so they do not release secretions into the duodenum.
E. Pancreas: The exocrine pancreas secretes digestive enzymes and bicarbonate into the duodenum via the pancreatic duct.
F. Intestinal glands: Intestinal glands (crypts of Lieberkühn) secrete intestinal juice directly into the intestinal lumen (including the duodenum), but the most commonly tested paired organs that "release secretions into the duodenum" are the liver (bile) and pancreas (pancreatic juice).

A. "It is an enzyme released into the duodenum.":Salivary amylase is secreted into the mouth; pancreatic amylase is released into the duodenum.
B. "It is an enzyme that breaks down the fats in breast milk.":Salivary amylase digests starches (carbohydrates); lingual lipase (and gastric/pancreatic lipases) act on fats.
C. "It is an enzyme that initiates the breakdown of carbohydrates.":Salivary amylase begins starch digestion in the oral cavity by cleaving polysaccharides into smaller sugars.
D. "It is an enzyme that breaks down proteins in the stomach.":Proteolysis in the stomach is primarily by pepsin (a gastric enzyme), not salivary amylase.