The healthcare provider suspects a client may have Paget's disease based on clinical presentation. Which laboratory test should be ordered to aid in the diagnosis?
Serum calcium level
Erythrocyte sedimentation rate (ESR)
Alkaline phosphatase (ALP) level
Serum creatinine level
The Correct Answer is C
An elevated alkaline phosphatase (ALP) level is a common finding in patients with Paget's disease. ALP is an enzyme present in bone cells, and its increased activity is indicative of increased bone turnover and remodeling seen in Paget's disease.
a. Serum calcium level: Serum calcium levels may be affected in Paget's disease due to abnormal bone remodeling, but they are not specific enough to confirm the diagnosis on their own.
b. Erythrocyte sedimentation rate (ESR): The ESR is a marker of inflammation and is not specific to Paget's disease. While it may be elevated due to bone inflammation, it does not confirm the diagnosis.
d. Serum creatinine level: Serum creatinine levels are not directly related to the diagnosis of Paget's disease. They are typically assessed to evaluate kidney function.
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Related Questions
Correct Answer is C
Explanation
The increased bone turnover and remodeling in Paget's disease can cause warmth and erythema (redness) over the affected bones. This is due to the increased blood flow and metabolic activity in the affected areas.
a. Cool, clammy skin: Cool, clammy skin is not directly related to the increased bone turnover and remodeling in Paget's disease. It may be related to other factors, such as circulation or environmental conditions.
b. Pulsating chest pain: Pulsating chest pain is not a typical finding in Paget's disease. It may be related to other cardiac or respiratory conditions.
d. Enlarged skull circumference: An enlarged skull circumference is a common manifestation of Paget's disease, but it is not directly related to the increased bone turnover and remodeling. It results from excessive bone growth in the skull bones.
Correct Answer is B
Explanation
A potential complication of Paget's disease is an increased risk of pathologic fractures. The abnormal bone remodeling weakens the bones, leading to an increased susceptibility to fractures.
a. Hypertension: Hypertension is not a direct complication of Paget's disease. The condition primarily affects bone structures.
c. Hyperthyroidism: Hyperthyroidism is not associated with Paget's disease. It is a separate condition related to thyroid gland dysfunction.
d. Type 2 diabetes mellitus: Type 2 diabetes mellitus is not a complication of Paget's disease. The conditions are unrelated and have different underlying causes.
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