The healthcare provider suspects a client may have Paget's disease based on clinical presentation. Which laboratory test should be ordered to aid in the diagnosis?
Serum calcium level
Erythrocyte sedimentation rate (ESR)
Alkaline phosphatase (ALP) level
Serum creatinine level
The Correct Answer is C
An elevated alkaline phosphatase (ALP) level is a common finding in patients with Paget's disease. ALP is an enzyme present in bone cells, and its increased activity is indicative of increased bone turnover and remodeling seen in Paget's disease.
a. Serum calcium level: Serum calcium levels may be affected in Paget's disease due to abnormal bone remodeling, but they are not specific enough to confirm the diagnosis on their own.
b. Erythrocyte sedimentation rate (ESR): The ESR is a marker of inflammation and is not specific to Paget's disease. While it may be elevated due to bone inflammation, it does not confirm the diagnosis.
d. Serum creatinine level: Serum creatinine levels are not directly related to the diagnosis of Paget's disease. They are typically assessed to evaluate kidney function.
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Related Questions
Correct Answer is A
Explanation
X-rays are the most useful imaging modality for assessing the extent and severity of bone involvement in Paget's disease. X-rays can reveal the characteristic bony overgrowth and thickening, as well as any bone deformities and fractures.
b. Computed tomography (CT) scan: CT scans can provide detailed images of bones and soft tissues, but they may not be the initial choice for evaluating Paget's disease. X-rays are more specific for the condition.
c. Magnetic resonance imaging (MRI): While an MRI can provide detailed images of bones and soft tissues, it may not be the first-line imaging choice for evaluating Paget's disease. X-rays are more specific for bone involvement.
d. Bone densitometry (DXA scan): Bone densitometry is used to assess bone mineral density and is commonly used for conditions like osteoporosis. It may not provide the necessary information for evaluating Paget's disease.
Correct Answer is B
Explanation
Calcium and vitamin D help reduce the risk of bone fractures in Paget's disease.
Explanation: Adequate calcium and vitamin D intake are essential for maintaining bone health and reducing the risk of bone fractures, especially in individuals with Paget's disease. While these nutrients do not cure Paget's disease, they play a crucial role in supporting bone strength and density.
a. Calcium and vitamin D can prevent the development of Paget's disease: This statement is incorrect. Paget's disease is primarily a result of genetic factors, and calcium and vitamin D intake do not prevent its development.
c. Calcium and vitamin D can cure Paget's disease: This statement is incorrect. While calcium and vitamin D are important for bone health, they do not cure Paget's disease. Treatment usually involves medications to manage the condition.
d. Calcium and vitamin D decrease bone turnover in Paget's disease: This statement is not entirely accurate. Calcium and vitamin D do not directly decrease bone turnover in Paget's disease. Medications like bisphosphonates are prescribed to address bone remodeling.
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