The nurse educator is reviewing hepatotoxicity for an in-service.
Which of the following should the nurse NOT include for in-service?
When two or more medications that are hepatotoxic are combined, the risk for liver damage is increased.
Damage to the liver cells can impair the metabolism of many medications, causing medication accumulation in the body and producing adverse effects.
When two or more medications that are hepatotoxic are combined, the risk for liver damage is decreased.
Manifestations of hepatotoxicity include nausea, vomiting, jaundice, dark urine, abdominal discomfort, and anorexia.
The Correct Answer is C
Choice A rationale
Combining multiple hepatotoxic medications increases the risk of liver damage due to cumulative toxicity effects.
Choice B rationale
Liver damage impairs the liver's ability to metabolize medications, leading to medication accumulation and potential adverse effects.
Choice C rationale
Combining hepatotoxic medications does not decrease the risk of liver damage; it increases it, as multiple toxic agents compound the stress on the liver.
Choice D rationale
Common manifestations of hepatotoxicity include symptoms like nausea, vomiting, jaundice, dark urine, abdominal discomfort, and anorexia, indicating liver dysfunction.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A rationale
Furosemide is a loop diuretic that acts on the ascending limb of the loop of Henle, not the distal tubule.
Choice B rationale
Spironolactone is a potassium-sparing diuretic that works on the collecting ducts and late distal tubules, not the distal tubule.
Choice C rationale
Mannitol is an osmotic diuretic that acts on the proximal tubule and the descending limb of the loop of Henle, not the distal tubule.
Choice D rationale
Hydrochlorothiazide is a thiazide diuretic that works on the distal convoluted tubule, making it the correct answer.
Correct Answer is A
Explanation
Choice A rationale
Waiting at least 5 minutes between puffs allows the first dose to take effect, optimizing absorption and reducing side effects when different inhaled medications are used.
Choice B rationale
Waiting 10 minutes between puffs is unnecessary and might reduce adherence to treatment due to the prolonged interval.
Choice C rationale
"None of the above" does not provide a valid education point for using metered-dose inhalers.
Choice D rationale
"All of the above" is incorrect as it includes a recommendation that is not necessary (waiting 10 minutes). .
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