The nurse is caring for a client who has thrombocytopenia.
Which of the following will the nurse administer for this disorder?

Corticosteroid.

Diphenhydramine.

Desmopressin (DDAVP).

Hydrochlorothiazide (HCTZ).

Answer and Explanation

The Correct Answer is A

Choice A rationale

Corticosteroids are used in thrombocytopenia because they suppress the immune response, particularly in immune thrombocytopenic purpura (ITP). They reduce platelet destruction by inhibiting autoantibody formation and increasing platelet lifespan. Normal platelet count ranges from 150,000 to 400,000/µL. Thrombocytopenia occurs when platelets drop below 150,000/µL, increasing bleeding risk. Corticosteroids can also decrease capillary permeability, minimizing petechiae and ecchymoses.

Choice B rationale

Diphenhydramine, an antihistamine, is used for allergic reactions but has no role in treating thrombocytopenia. It does not address the underlying immune or hematologic causes of low platelet counts. Its primary actions include H1 receptor antagonism, reducing histamine-mediated symptoms like itching and swelling. However, it lacks immunosuppressive or hematologic-stimulating effects essential for managing thrombocytopenia.

Choice C rationale

Desmopressin (DDAVP) is a synthetic antidiuretic hormone analog used for certain bleeding disorders like von Willebrand disease or mild hemophilia A. It increases factor VIII and von Willebrand factor levels, improving clotting. However, it is not indicated for thrombocytopenia as it does not address platelet count deficiencies or immune-mediated platelet destruction.

Choice D rationale

Hydrochlorothiazide (HCTZ) is a thiazide diuretic used for hypertension and edema. Its mechanism of action involves inhibiting sodium reabsorption in the distal tubule, promoting diuresis. HCTZ has no effect on platelet counts or immune mechanisms and is not used in thrombocytopenia. Its side effects, like electrolyte imbalances, may complicate patient management.

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Correct Answer is C

Explanation

Choice A rationale

Ecchymosis and wet purpura indicate abnormal bleeding tendencies often observed in platelet defects. While these findings are relevant, they are secondary to identifying medications that could exacerbate platelet dysfunction. Medication history directly influences the management plan by addressing reversible causes of thrombocytopenia, emphasizing its priority over descriptive bleeding symptoms.

Choice B rationale

Upcoming dental or invasive procedures are relevant to thrombocytopenia risks due to potential bleeding complications. However, these appointments do not provide immediate insight into causative factors of the platelet defect. Determining medication use offers direct information regarding drug-related impacts on platelet function, prioritizing it for management and diagnostic purposes over procedural risks.

Choice C rationale

Over-the-counter and prescription medication use are critical to evaluate because certain drugs can induce or worsen platelet defects. For example, NSAIDs like aspirin inhibit platelet aggregation and contribute to bleeding risks. Establishing this information helps guide management by identifying reversible causes and reducing complications associated with defective platelet function.

Choice D rationale

Family and genetic history offer valuable insights into inherited platelet disorders but are less immediately actionable for addressing acute platelet defects. Medications causing or contributing to thrombocytopenia present modifiable factors, prioritizing their identification over hereditary predispositions. Addressing medication-induced platelet dysfunction provides practical management strategies for preventing bleeding complications. .

Correct Answer is ["12"]

Explanation

Step 1 is (176 pounds ÷ 2.2 pounds/kg) × 10 mcg/kg/min = 800 mcg/min.

Step 2 is (800 mcg ÷ 1000 mcg/mg) × 250 mL = 0.2 mL/min.

Step 3 is 0.2 mL/min × 60 min = 12 mL/hour. Final answer: 12 mL/hour.

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The nurse is caring for a client who has thrombocytopenia.Which of the following will the nurse administer for this disorder?

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Naxlex Comprehensive Predictor Exams

The nurse is obtaining the health history from a client who was admitted with a platelet defect.Which of the following information should be a priority for the nurse to obtain?

Correct Answer is C

Explanation

The nurse is caring for a client who is in heart failure and weighs 176 pounds. The client is to receive prescribed dobutamine 10 mcg/kg/minute. The nurse has available 1,000 mg in 250 mL of 0.9% normal saline. How many mL per hour should the nurse administer to the client?

Correct Answer is ["12"]

Explanation

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The nurse is caring for a client who has thrombocytopenia.
Which of the following will the nurse administer for this disorder?