The nurse is caring for a client who has thrombocytopenia.
Which of the following will the nurse administer for this disorder?
Corticosteroid.
Diphenhydramine.
Desmopressin (DDAVP).
Hydrochlorothiazide (HCTZ).
The Correct Answer is A
Choice A rationale
Corticosteroids are used in thrombocytopenia because they suppress the immune response, particularly in immune thrombocytopenic purpura (ITP). They reduce platelet destruction by inhibiting autoantibody formation and increasing platelet lifespan. Normal platelet count ranges from 150,000 to 400,000/µL. Thrombocytopenia occurs when platelets drop below 150,000/µL, increasing bleeding risk. Corticosteroids can also decrease capillary permeability, minimizing petechiae and ecchymoses.
Choice B rationale
Diphenhydramine, an antihistamine, is used for allergic reactions but has no role in treating thrombocytopenia. It does not address the underlying immune or hematologic causes of low platelet counts. Its primary actions include H1 receptor antagonism, reducing histamine-mediated symptoms like itching and swelling. However, it lacks immunosuppressive or hematologic-stimulating effects essential for managing thrombocytopenia.
Choice C rationale
Desmopressin (DDAVP) is a synthetic antidiuretic hormone analog used for certain bleeding disorders like von Willebrand disease or mild hemophilia A. It increases factor VIII and von Willebrand factor levels, improving clotting. However, it is not indicated for thrombocytopenia as it does not address platelet count deficiencies or immune-mediated platelet destruction.
Choice D rationale
Hydrochlorothiazide (HCTZ) is a thiazide diuretic used for hypertension and edema. Its mechanism of action involves inhibiting sodium reabsorption in the distal tubule, promoting diuresis. HCTZ has no effect on platelet counts or immune mechanisms and is not used in thrombocytopenia. Its side effects, like electrolyte imbalances, may complicate patient management.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Improved tolerance for daily activities suggests increased energy levels and improved oxygen delivery to tissues, both indicative of effective iron deficiency anemia treatment. Normal hemoglobin levels are 12-16 g/dL for females and 14-18 g/dL for males, supporting enhanced activity tolerance.
Choice B rationale
Decreased paresthesia indicates improved nerve function but is not directly linked to iron deficiency anemia treatment outcomes. Iron deficiency primarily impacts oxygen transport, and improvements in energy levels and activity tolerance are better indicators of therapeutic success.
Choice C rationale
Improved white blood cell count suggests better immune function but does not directly assess anemia treatment efficacy. Iron therapy aims to normalize hemoglobin and hematocrit levels rather than leukocyte parameters, which are unrelated to anemia management.
Choice D rationale
Enhanced balance may indicate improved neuromuscular function but is not directly correlated with anemia treatment. Balance is influenced by multiple factors, including neurological or musculoskeletal health, rather than oxygenation improvements specific to anemia.
Correct Answer is D
Explanation
Choice A rationale
Hypotension is not a typical sign of fluid overload. Fluid overload often presents with hypertension due to increased circulatory volume. Monitoring blood pressure is essential, but hypotension does not reliably indicate fluid overload. This option does not align with scientific understanding of fluid overload symptoms.
Choice B rationale
Distention above the pubis area suggests urinary retention or bladder distension rather than fluid overload. While important to assess, it does not directly indicate fluid overload. This symptom is more related to mechanical issues than systemic fluid imbalance and volume overload.
Choice C rationale
Hypernatremia is not a sign of fluid overload. Fluid overload typically results in dilutional hyponatremia, where excessive fluids lower sodium levels. Monitoring sodium levels is useful, but hypernatremia would suggest dehydration or other conditions, not excess fluid volume. This choice is inconsistent with scientific knowledge.
Choice D rationale
Maintaining strict intake and output records is a fundamental approach to monitoring fluid balance. Accurate measurements of fluid intake and output help detect fluid overload early. This method directly correlates with assessing excess fluid volume in clinical practice. It is a reliable, evidence-based intervention for monitoring fluid status. .
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