The nurse is teaching a group of parents about the use of syrup of ipecac.
Which instruction will the nurse provide?

Choice A rationale

Working with animals is typically done in preclinical trials before phase I studies in humans and is not part of phase III drug evaluation studies.

Choice B rationale

Conducting research to determine the effectiveness of the drug is part of phase II studies. Phase III studies focus more on confirming effectiveness, monitoring side effects, and comparing it to commonly used treatments.

Choice C rationale

Monitoring and observing patients closely for adverse effects is a key responsibility in phase III drug evaluation studies. These studies involve a larger patient population to gather comprehensive safety and efficacy data.

Choice D rationale

Choosing appropriate patients to be involved in the study is primarily the responsibility of researchers and clinicians during the earlier phases of drug development, such as phase I and phase II studies.

Choice A rationale

The small intestine is where nutrients are absorbed, but it is not where vitamin D is activated. Vitamin D is first converted in the liver and then activated in the kidneys to promote calcium absorption.

Choice B rationale

This is incorrect because vitamin D is activated into a form that promotes calcium absorption. The active form is crucial for maintaining calcium and phosphate levels in the blood.

Choice C rationale

The kidneys play a significant role in converting vitamin D to its active form, calcitriol. This activated form is essential for the absorption of calcium in the intestines.

Choice D rationale

The large intestine is involved in water absorption and waste formation but not in the activation of vitamin D. The activation process primarily occurs in the kidneys and liver. .