The nurse knows the rationale for combination chemotherapy is to:

limit episodes of anticipatory and delayed emesis

lessen the client's risk of developing neutropenia

decrease time intervals between remission

broaden range of cell kill while minimizing toxicities to the client

Answer and Explanation

The Correct Answer is D

A. While limiting emesis is important in cancer treatment, combination chemotherapy primarily focuses on improving efficacy and minimizing toxicities, not specifically targeting nausea and vomiting episodes.
B. Combination chemotherapy can actually increase the risk of neutropenia due to the cumulative effects of multiple agents, as each may independently lower white blood cell counts.
C. Decreasing time intervals between remission is not a primary goal of combination chemotherapy; rather, it aims to achieve better overall treatment outcomes.
D. The main rationale for using combination chemotherapy is to broaden the range of cancer cell kill through different mechanisms of action while minimizing the side effects associated with higher doses of a single agent. This approach can improve treatment efficacy and reduce the likelihood of resistance.

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Correct Answer is C

Explanation

A. Slowing the rate of infusion may provide some temporary relief, but it does not address the underlying issue and may worsen the situation.
B. Applying a warm compress may soothe discomfort but is not the priority action when a burning sensation is reported, which could indicate potential extravasation.
C. Discontinuing the infusion is the best first action to prevent further damage to the tissue and to assess for complications such as infiltration or extravasation.
D. Checking for blood return can help assess the patency of the IV line, but the priority is to stop the infusion immediately to prevent complications.

A. Assessing pupils for reactivity, equality, symmetry, and accommodation B. Obtaining vital signs every four hours while hospitalized C. Performing serial Glasgow Coma Scales throughout hospitalization D. Performing a Mini Mental Status Exam at admission and discharge

Correct Answer is C

Explanation

A. Assessing pupils is important, but it provides only partial information about the overall neurologic status and does not give a comprehensive picture of improvement or deterioration.
B. Vital signs can indicate some changes in condition but are not specific to neurologic status and do not provide detailed insight into cognitive or motor function.
C. Performing serial Glasgow Coma Scales allows for a standardized and objective assessment of a patient's level of consciousness, motor responses, and verbal responses over time, making it the most effective method to evaluate neurologic status.
D. The Mini Mental Status Exam provides useful information about cognitive function but may not capture acute changes in neurologic status as effectively as the Glasgow Coma Scale.

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Electrolyte	Normal Value Range
Serum sodium	135-145 mEq/L
Serum chloride	97-107 mEq/L
Serum potassium	3.5-5:3 mEq/L
Serum magnesium	1.6-2.2 mg/dL
Total serum calcium	8.2-10.2 mg/dL
lonized calcium	4.6-5.3 mg/dL
Serum phosphorus	2.5-4.5 mg/dL
Serum osmolality	275-295 mOsm/kg
Urine osmolality	250-900 mOsm/kg

The nurse knows the rationale for combination chemotherapy is to:

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A client, who is receiving intravenous chemotherapy into a peripheral vein, says that the arm burns terribly in and around the intravenous site. What is the nurse's best first action?

Correct Answer is C

Explanation

The nurse is performing an assessment on a patient. How would the nurse best evaluate improvement or deterioration in the neurologic status?

Correct Answer is C

Explanation

A jaundiced client has just been diagnosed with stage IV pancreatic cancer. The nurse anticipates the client will display which clinical manifestation?

The nurse caring for a client diagnosed with pancreatic cancer understands that the key to effective pain management is: (SELECT ALL THAT APPLY)

A physician prescribes Vancomycin 20 mg/kg IV. The client weighs 110 lbs. The medication is available in vials which contain 500 mg per 8 mL. What should the nurse withdraw from the vial?

In assessing a client with esophageal cancer being treated with radiation therapy, which finding(s) would alert the nurse to a possible side effect of this treatment?

The nurse notes serosanguinous drainage from the nasogastric tube in the immediate postoperative period of a client who had a gastrectomy for gastric cancer. Which nursing action is appropriate?

The nurse is aware that radiation therapy is most effective for which type of client? A client who has cancer which is:

A client has numerous skin lesions. Which one will the nurse evaluate first?