The patient is taking low-dose aspirin daily for his heart. The nurse knows only a portion of the medication taken actually reaches the tissue due to what process?
Distribution
First-pass effect
Reduced absorption
Gastrointestinal circulation
The Correct Answer is B
A. Distribution refers to the movement of the drug from the bloodstream into tissues and organs, but it does not explain why only a portion of the medication reaches the tissues.
B. The first-pass effect occurs when an orally administered drug is metabolized by the liver before reaching systemic circulation. Aspirin, when taken orally, undergoes significant metabolism in the liver, reducing the amount of active drug available to exert its therapeutic effect. This explains why only a portion of the drug reaches the tissues.
C. Reduced absorption can limit drug availability, but aspirin is generally well absorbed in the gastrointestinal tract. The primary reason for reduced drug availability in this case is metabolism by the liver, not poor absorption.
D. Gastrointestinal circulation involves the enterohepatic recycling of some drugs, but it does not explain why only a portion of aspirin reaches systemic circulation. The first-pass effect is the primary factor.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
a) The six rights of medication administration—right patient, right medication, right dose, right route, right time, and right documentation—help ensure patient safety by reducing medication errors. This is a fundamental nursing practice to prevent adverse drug reactions, overdoses, or omissions.
b) Informed consent is important but is not directly related to the six rights of medication administration. It is typically obtained before administering high-risk medications or treatments.
c) While proper medication administration includes patient education, the six rights primarily focus on safety rather than the adequacy of information given.
d) The six rights do not focus on cost-effectiveness but rather on the accurate and safe administration of drugs.
Correct Answer is B
Explanation
A. While medication adherence is important, the primary reason for asking about alternative therapies is not due to concerns about compliance. Patients may use alternative therapies alongside prescribed medications, potentially leading to harmful interactions.
B. Many complementary and alternative therapies, such as herbal supplements, can interact with prescribed medications, leading to adverse effects or reduced drug efficacy. For example, St. John’s Wort can decrease the effectiveness of certain medications, including anticoagulants and antidepressants. Identifying these therapies ensures patient safety.
C. While some natural products may have therapeutic benefits, they are not necessarily more effective than prescribed medications. Healthcare providers should base treatment decisions on evidence-based practice rather than assuming an alternative therapy is superior.
D. Financial concerns are important but not the primary reason for inquiring about alternative therapies. The nurse’s main concern is the potential for harmful drug interactions rather than the cost burden on the patient.
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