The primary factor responsible for possible multiple clinical manifestations in cystic fibrosis is which of the following?
Hyperactivity of sweat glands
Mechanical obstruction caused by increased viscosity of mucous gland secretion
Hypoactivity of autonomic nervous system
Atrophic changes in mucosal wall of intestines
The Correct Answer is B
A. Hyperactivity of sweat glands:
In cystic fibrosis (CF), there is an abnormality in the CF transmembrane conductance regulator (CFTR) protein, leading to increased salt concentration in sweat. However, this is not the primary factor responsible for the diverse clinical manifestations in CF. The primary issue lies in the abnormal production of thick and sticky mucus affecting various organs.
B. Mechanical obstruction caused by increased viscosity of mucous gland secretion:
This is the correct choice. CF is characterized by the production of thick and sticky mucus due to abnormal CFTR protein function. This increased viscosity leads to mechanical obstruction in organs such as the respiratory, digestive, and reproductive systems, causing a range of clinical manifestations.
C. Hypoactivity of the autonomic nervous system:
CF is not characterized by hypoactivity of the autonomic nervous system. The primary issue lies in the mechanical obstruction caused by the abnormal mucus production.
D. Atrophic changes in the mucosal wall of the intestines:
Atrophic changes in the mucosal wall of the intestines are not the primary factor responsible for the clinical manifestations of CF. The key problem is the mechanical obstruction due to increased viscosity of mucous gland secretions.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. 21 pounds: This is the correct answer. The general guideline is that infants tend to triple their birth weight by the age of 12 months. If the infant weighed 7 pounds at birth, tripling that weight would be 21 pounds.
B. 14 pounds: This weight would not be consistent with the expected weight gain of a healthy infant by 12 months. It's too low based on the tripling guideline.
C. 25 pounds: This weight would be higher than expected based on the tripling guideline. It's not a typical weight for a healthy 12-month-old who had a birth weight of 7 pounds.
D. 10 pounds: This weight would be lower than the expected weight gain. A 12-month-old who started at 7 pounds should have gained more weight by this age.
Correct Answer is D
Explanation
A. Bronchiolitis:
Bronchiolitis is typically characterized by inflammation of the bronchioles, causing symptoms such as wheezing and respiratory distress. However, the symptom of tasting salt on the skin is not directly associated with bronchiolitis.
B. Pharyngitis:
Pharyngitis, or inflammation of the throat, may cause symptoms like a sore throat, but it is not typically associated with a salty taste on the skin.
C. Asthma:
Asthma is a chronic condition characterized by airway inflammation and bronchoconstriction. While it can cause respiratory symptoms, it is not specifically associated with a salty taste on the skin.
D. Cystic Fibrosis:
Cystic Fibrosis is a genetic disorder that affects the respiratory, digestive, and reproductive systems. It often leads to salty-tasting skin due to increased salt content in sweat. The presence of a salty taste on the skin can be a significant indicator of cystic fibrosis.
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