What factors can influence drug absorption? (Select all that apply)

Lung function

Kidney function

Liver function

Route of administration

Answer and Explanation

The Correct Answer is C

a) Lung function primarily affects gas exchange and respiratory function but does not significantly influence drug absorption.

b) Kidney function is important for drug excretion rather than absorption. It impacts drug elimination and toxicity risk rather than how well a drug is absorbed.

c) Liver function plays a key role in drug metabolism. Poor liver function can alter drug absorption and metabolism, particularly for orally administered drugs that undergo the first-pass effect.

d) The route of administration directly impacts drug absorption. For example, intravenous (IV) drugs bypass absorption entirely, while oral medications must go through the digestive system before entering circulation.

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Correct Answer is A

Explanation

a) Pregnancy Category B drugs are those for which animal studies have not shown harm to the fetus, but there are no well-controlled studies in pregnant women. This means that while the drug appears to be safe in animal models, its effects on human pregnancy remain uncertain.

b) This statement describes Pregnancy Category A, where adequate human studies have shown no risk to the fetus.

c) This statement describes Pregnancy Category D, where there is clear evidence of human fetal risk, but benefits may outweigh risks in certain situations.

d) This statement describes Pregnancy Category C, where animal studies have shown adverse effects, but there are no adequate human studies, and the drug may still be used if the benefits outweigh the risks.

A. C-V B. C-II C. C-I D. C-III

Correct Answer is B

Explanation

A. C-V drugs are considered to have the lowest potential for abuse and are typically used for medications like cough preparations with less than 200 milligrams of codeine per 100 milliliters or per 100 grams. Methadone is not classified under C-V.

B. Methadone is classified as a C-II (Schedule II) controlled substance because it has a high potential for abuse, but it also has accepted medical uses, such as for opioid withdrawal management.

C. C-I drugs are considered to have no accepted medical use and a high potential for abuse (e.g., heroin, LSD). Methadone is not classified as a C-I drug.

D. C-III drugs have a moderate potential for abuse and are generally used for medications like anabolic steroids or some barbiturates, but methadone is not classified under C-III.

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What factors can influence drug absorption? (Select all that apply)

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is instructing a pregnant patient concerning the potential risk to her fetus from a Pregnancy Category B drug. The nurse would inform the patient that:

Correct Answer is A

Explanation

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Correct Answer is B

Explanation

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