What is a potential complication of Paget's disease?

Bisphosphonates are commonly used as the first-line treatment for Paget's disease. They work by slowing down bone resorption and promoting more balanced bone remodeling, helping to control the excessive bone turnover characteristic of the condition.

a. Calcium supplements: While calcium supplements are essential for overall bone health, they are not the first-line treatment for Paget's disease. Bisphosphonates specifically target the abnormal bone remodeling associated with the condition.

b. Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs may help manage pain and inflammation associated with Paget's disease, but they do not directly address the underlying bone remodeling abnormalities. Bisphosphonates are more effective in treating the condition.

d. Vitamin D supplements: Vitamin D is necessary for calcium absorption and bone health, but it is not the primary treatment for Paget's disease. Bisphosphonates are the mainstay of therapy.

Paget's disease is a metabolic bone disorder that involves abnormal bone remodeling, leading to areas of increased bone density and disorganized bone formation. It is not a genetic disorder, autoimmune disease, or neurological disorder.

a. A genetic disorder characterized by abnormal bone density: While Paget's disease has a genetic component, it is not solely a genetic disorder. The condition involves both genetic and environmental factors.

b. An autoimmune disease affecting the joints and connective tissues: Paget's disease is not an autoimmune disease. It primarily affects bone structures, not joints and connective tissues.

d. A degenerative neurological disorder causing muscle weakness: Paget's disease is not a neurological disorder. It does not directly affect the nervous system or cause muscle weakness.