Which is the treatment of choice for severe aplastic anemia?

Bone marrow transplantation

Exchange transfusion

Liver transplantation

Administration of intravenous immunoglobulin

Answer and Explanation

The Correct Answer is A

A. Bone marrow transplantation.

Severe aplastic anemia is a condition characterized by a significant reduction in the number of blood cells produced by the bone marrow. The primary treatment for severe aplastic anemia is a bone marrow transplantation, also known as a stem cell transplant. This procedure involves replacing the patient's dysfunctional bone marrow with healthy bone marrow or stem cells from a suitable donor. This is done to restore normal blood cell production.

Option B (Exchange transfusion) is not the primary treatment for severe aplastic anemia but may be used in certain cases to manage complications or specific symptoms.

Option C (Liver transplantation) is not a treatment for severe aplastic anemia, as this condition primarily affects the bone marrow and blood cell production.

Option D (Administration of intravenous immunoglobulin) is not the primary treatment for severe aplastic anemia but may be used in some cases to manage complications, such as infections. However, it does not address the underlying cause of the disease, which is the failure of the bone marrow to produce enough blood cells.

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Correct Answer is C

Explanation

In transposition of the great vessels (TGV), the aorta and the pulmonary artery are switched, causing oxygen-rich blood to be pumped back to the lungs and oxygen-poor blood to be pumped out to the body. The ductus arteriosus, a fetal blood vessel that normally closes shortly after birth, allows blood to mix between the two circulations.

Prostaglandin E1 is used to keep the ductus arteriosus open, allowing for a controlled mixing of oxygenated and deoxygenated blood, which can improve oxygen delivery to the body in cases of TGV. This helps maintain oxygenation until corrective surgical interventions can be performed.

The other options, A (decrease pulmonary congestion), B (stimulate the production of red blood cells), and D (increase blood flow to the system), do not accurately describe the primary purpose of Prostaglandin E1 in the context of TGV. The main goal is to maintain a pathway for oxygenated blood to mix with deoxygenated blood to improve oxygen delivery to the body.

A. Inspect the mouth weekly for ulcerations B. Use a potent commercial mouthwash C. Clean the teeth manually with a soft toothbrush D. Visit a dental professional only during episodes of excessive bleeding or pain

Correct Answer is C

Explanation

A. Inspecting the mouth weekly for ulcerations is not sufficient. Children receiving chemotherapy should be encouraged to perform daily oral care, and any concerning symptoms should be reported promptly to the healthcare provider.

B. Using a potent commercial mouthwash is not recommended, as many commercial mouthwashes contain alcohol or other potentially irritating ingredients. A healthcare provider should recommend a suitable oral rinse if needed.

C. Clean the teeth manually with a soft toothbrush.

Children receiving chemotherapy are at risk of developing mouth sores (mucositis) and other oral complications. It is essential to maintain good oral hygiene to minimize the risk of infection and reduce discomfort. Using a soft toothbrush for gentle manual cleaning is recommended, as it helps to prevent injury to the sensitive oral tissues that can occur with a hard toothbrush.

D. Visiting a dental professional only during episodes of excessive bleeding or pain is not recommended. Regular dental check-ups are important for children receiving chemotherapy to monitor and address oral health issues. Waiting for symptoms of bleeding or pain may result in a delay in addressing potential problems.

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Which is the treatment of choice for severe aplastic anemia?

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Naxlex Comprehensive Predictor Exams

The nurse explains that the medication Prostaglandin E1 is being given to their child with transposition of the great vessels to:

Correct Answer is C

Explanation

The nurse would include in a teaching plan about mouth care for a child receiving chemotherapy to:

Correct Answer is C

Explanation

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