Which of the following is a common clinical manifestation of Paget's disease?

Paget's disease has a genetic component, and there is evidence of familial inheritance. Individuals with a family history of Paget's disease are at a higher risk of developing the condition.

b. It is caused by vitamin D deficiency: Paget's disease is not caused by vitamin D deficiency. It is primarily a result of genetic factors leading to abnormal bone remodeling.

c. It primarily affects the hands and feet: Paget's disease can affect various bones in the body, not just the hands and feet. It commonly involves the pelvis, vertebrae, and ribs.

d. It is a rare condition with a prevalence of less than 1%: Paget's disease is not considered rare. It is relatively common, particularly in older adults, with a prevalence estimated to be around 1-3% in individuals over the age of 40.

The goal of treatment for Paget's disease is to relieve pain and prevent complications associated with bone deformities and fractures. There is no cure for Paget's disease, but treatment aims to manage symptoms and reduce the risk of complications.
a. Cure the disease completely: Paget's disease is a chronic condition with no known cure. Treatment focuses on symptom management and preventing complications.
c. Restore normal bone density: While treatment may aim to reduce abnormal bone remodeling, restoring normal bone density is not typically achievable. The focus is on pain relief and preventing complications.
d. Regenerate damaged bones: While treatment may improve bone health and reduce deformities, regenerating damaged bones to their original state is not feasible. Treatment aims to manage the disease and its consequences effectively.