Which of the following phases of pharmacokinetics is described as the removal of the drug or its metabolites through the kidneys, gastrointestinal tract, skin, or lungs?

Distribution

Metabolism

Absorption

Excretion

Answer and Explanation

The Correct Answer is D

A.   Distribution: This phase involves the transportation of the drug throughout the body after absorption, not removal.
B.   Metabolism: This phase involves the chemical alteration of the drug in the body, often in the liver, not its removal.
C.   Absorption: This phase involves the drug entering the bloodstream after administration.
D.   Excretion: This is the phase where the drug or its metabolites are removed from the body through various routes such as the kidneys, gastrointestinal tract, skin, or lungs.

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Correct Answer is A

Explanation

A. NPH insulin is an intermediate-acting insulin that is administered via the subcutaneous route to manage blood sugar levels in clients with diabetes.
B. Regular insulin is a short-acting insulin that can be administered subcutaneously to control blood glucose levels in clients with type 2 diabetes.
C. This is an oral medication, not a parenteral (injected) medication. It is an oral sulfonylurea used to manage blood glucose in type 2 diabetes.
D. Metformin is also an oral medication used to treat type 2 diabetes and is not administered subcutaneously.

A. Celecoxib Celebrex B. Morphine sulfate (Astramorph) C. Metformin (Glucophage) D. Ibuprofen (Motrin)

Correct Answer is D

Explanation

Rationale
A. Celecoxib is a second-generation NSAID that specifically inhibits COX-2 enzymes and is less likely to cause gastrointestinal side effects compared to first-generation NSAIDs.
B. Morphine sulfate is an opioid analgesic and does not have NSAID properties. It works by binding to opioid receptors to relieve pain.
C. Metformin is an oral medication used to manage blood glucose in type 2 diabetes and is not an NSAID.
D. Ibuprofen is a first-generation NSAID that inhibits both COX-1 and COX-2 enzymes, reducing pain, inflammation, and fever.

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Which of the following phases of pharmacokinetics is described as the removal of the drug or its metabolites through the kidneys, gastrointestinal tract, skin, or lungs?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

Which of the following medications are parenteral anti-diabetic medications used to treat clients with type 2 diabetes mellitus that are administered via the subcutaneous route? (Select All That Apply.).

Correct Answer is A

Explanation

The nurse is providing an in-service on non-steroidal anti-inflammatory drugs (NSAIDs). Which of the following medications is a first-generation NSAID that inhibits both COX-1 and COX-2 enzymes?

Correct Answer is D

Explanation

A client is being admitted for hypernatremia. A nurse is preparing to administer 0.45% sodium chloride 500 mL IV to the client over 2 hours. The nurse should set the IV pump to deliver how many mL/hr?

A client has a new prescription of spironolactone (Aldactone), and wants to learn about how the mechanism of action of this medication. Which of the following statements should the nurse explain to the client?

A nurse is educating the client about the baclofen. Which of the following responses is a therapeutic use of baclofen?

A nurse is teaching diabetic clients about the use of insulin. For which of the following types of insulin should the nurse tell the clients to expect an onset of 15 to 30 minutes?

The nurse is providing an in-service on mucosal protectants. What medication protects the ulcer from further injury from acid and pepsin and is a viscous substance that can stick to the ulcer for up to 6 hours?

The client has been prescribed acetylsalicylic acid (Aspirin) by the healthcare provider. However, the client is not sure about the uses of aspirin. What of the following are the appropriate indications for aspirin? (Select All That Apply.).

A nurse is providing teaching to a female client who is taking conjugated equine estrogens (Premarin). Which of the following clients are contraindicated for conjugated equine estrogens (Premarin)? (Select All That Apply).

The nurse teaches a patient with chronic obstructive pulmonary disease (COPD) about pursed-lip breathing (PLB). Which action by the patient would indicate to the nurse that no further teaching is needed?