Which of the following responses indicate that the nurse understands the first-pass effect?
Medication routes that are affected by the first-pass effect include intravenous, intramuscular, and intradermal.
Enteric-coated tablets and capsules are affected by the first-pass effect except a pharmacologic effect.
The first-pass effect is when the liver activates all medications on their first pass through the liver.
Enteral medications may need a higher dose due to the first-pass effect.
The Correct Answer is D
Choice A rationale
Intravenous, intramuscular, and intradermal routes bypass the first-pass effect as they do not pass through the liver first.
Choice B rationale
Enteric-coated tablets and capsules are designed to bypass the stomach and dissolve in the intestines, reducing the first-pass effect.
Choice C rationale
The first-pass effect involves the liver metabolizing and inactivating a portion of the medication on its first pass through the liver.
Choice D rationale
Enteral medications, which pass through the digestive system, may require higher doses due to the first-pass effect where the liver metabolizes the medication before it reaches systemic circulation. .
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["B","C"]
Explanation
Choice A rationale
Tamsulosin is used to relax the muscles in the prostate and bladder neck, making it easier to urinate in men with BPH.
Choice B rationale
Sildenafil is primarily used to treat erectile dysfunction and pulmonary hypertension. It is not used to treat BPH.
Choice C rationale
Ethinyl estradiol and drospirenone are components of oral contraceptives and are not used for the treatment of BPH.
Choice D rationale
Finasteride is used to shrink an enlarged prostate by blocking the hormone that causes prostate growth, making it a common treatment for BPH.
Correct Answer is B
Explanation
Choice A rationale
This statement is incorrect because an antagonist medication changes the effects of normal cellular functions by blocking receptors.
Choice B rationale
An antagonist medication binds to receptors and blocks the usual receptor activity, preventing the normal action of the endogenous substance.
Choice C rationale
This statement describes an agonist medication, which binds to receptors and increases the effects of normal cellular functions.
Choice D rationale
This statement is incorrect because an antagonist medication does not both increase and decrease the effects on normal cellular functions; it primarily blocks receptor activity.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.