A nurse is preparing to educate a patient who has newly been prescribed sucralfate (Carafate) for the management of peptic ulcer disease (PUD). What is the mechanism of action for this medication?

Neutralizes the acidity of the gastric acid.

Acts as an endogenous prostaglandin in the GI tract.

Antagonizes H2 receptors on parietal cells.

Creates a protective barrier that adheres to an ulcer, which can stick to the ulcer for up to 6 hours.

Answer and Explanation

The Correct Answer is D

A. Sucralfate does not neutralize gastric acid; antacids are responsible for neutralization.

B. Sucralfate does not mimic endogenous prostaglandins. Medications like misoprostol act as prostaglandins to protect the stomach lining.

C. Sucralfate does not block H2 receptors. Medications like cimetidine or ranitidine work through this mechanism to reduce acid production.

D. Sucralfate creates a viscous, protective barrier that adheres to the ulcer site, shielding it from further damage by gastric acid, bile, and pepsin for up to 6 hours, thereby promoting healing.

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Correct Answer is B

Explanation

A. Hypothyroidism: This is incorrect. The client is taking levothyroxine (Synthroid) to treat hypothyroidism, and the symptoms described (diarrhea, weight loss, palpitations, heat intolerance) are more likely associated with excess thyroid hormone, not a lack of it.

B. Thyrotoxicosis: This is correct. The symptoms the client is experiencing—diarrhea, weight loss, palpitations, and heat intolerance—are classic signs of thyrotoxicosis, which occurs when there is an excess of thyroid hormone, possibly due to overtreatment with levothyroxine. These symptoms indicate that the thyroid hormone dose might need adjustment.

C. Addison's Disease: This is incorrect. Addison's disease is characterized by insufficient production of adrenal hormones and would typically manifest with symptoms such as fatigue, hypotension, and hyperpigmentation, not diarrhea or heat intolerance.

D. Cushing's Disease: This is incorrect. Cushing's disease is caused by excess cortisol and would typically result in symptoms such as weight gain, high blood pressure, and a round "moon" face, rather than the symptoms described in the question.

Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"D"}

Explanation

Weight gain: Glipizide, like other sulfonylureas, can cause weight gain as it stimulates insulin secretion, which can lead to increased fat storage.

Hypoglycemia: One of the most common and serious side effects of glipizide is hypoglycemia, as it increases insulin levels, which can lower blood sugar too much

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A nurse is preparing to educate a patient who has newly been prescribed sucralfate (Carafate) for the management of peptic ulcer disease (PUD). What is the mechanism of action for this medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

You are caring for a client with hypothyroidism that is taking levothyroxine (Synthroid). The client reports diarrhea, weight loss, palpitations, and heat intolerance. You suspect which of the following adverse effects of this drug?

Correct Answer is B

Explanation

Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"D"}

Explanation

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