A nurse is preparing to educate a patient who has newly been prescribed sucralfate (Carafate) for the management of peptic ulcer disease (PUD). What is the mechanism of action for this medication?
Neutralizes the acidity of the gastric acid.
Acts as an endogenous prostaglandin in the GI tract.
Antagonizes H2 receptors on parietal cells.
Creates a protective barrier that adheres to an ulcer, which can stick to the ulcer for up to 6 hours.
The Correct Answer is D
A. Sucralfate does not neutralize gastric acid; antacids are responsible for neutralization.
B. Sucralfate does not mimic endogenous prostaglandins. Medications like misoprostol act as prostaglandins to protect the stomach lining.
C. Sucralfate does not block H2 receptors. Medications like cimetidine or ranitidine work through this mechanism to reduce acid production.
D. Sucralfate creates a viscous, protective barrier that adheres to the ulcer site, shielding it from further damage by gastric acid, bile, and pepsin for up to 6 hours, thereby promoting healing.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is {"dropdown-group-1":"A","dropdown-group-2":"C"}
Explanation
- Docusate sodium: This is a surfactant laxative that helps soften stools by allowing water and fats to penetrate the stool, making it easier to pass.
- Loperamide: This medication is an anti-diarrheal agent that works by slowing down gut movement, which helps reduce the frequency of diarrhea.
Correct Answer is D
Explanation
A. "This medication may cause increased libido." This is incorrect. Cimetidine (Tagamet) can cause side effects such as decreased libido, especially in men. This occurs because the drug inhibits the action of certain hormones, leading to sexual dysfunction.
B. "You may take this medication with antacids to prevent stomach upset." This is incorrect. Cimetidine should not be taken with antacids because antacids can reduce its absorption and effectiveness. It is advised to space the administration of cimetidine and antacids by at least 1 hour.
C. "This medication will neutralize your stomach acid." This is incorrect. Cimetidine works by blocking histamine receptors (H2 receptors), which reduces the production of stomach acid but does not neutralize it.
D. "This medication may cause decreased libido." This is correct. One of the side effects of cimetidine is reduced libido, particularly in male clients, due to its anti-androgenic effects.
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