A nurse is preparing to educate a patient who has newly been prescribed sucralfate (Carafate) for the management of peptic ulcer disease (PUD). What is the mechanism of action for this medication?
Neutralizes the acidity of the gastric acid.
Acts as an endogenous prostaglandin in the GI tract.
Antagonizes H2 receptors on parietal cells.
Creates a protective barrier that adheres to an ulcer, which can stick to the ulcer for up to 6 hours.
The Correct Answer is D
A. Sucralfate does not neutralize gastric acid; antacids are responsible for neutralization.
B. Sucralfate does not mimic endogenous prostaglandins. Medications like misoprostol act as prostaglandins to protect the stomach lining.
C. Sucralfate does not block H2 receptors. Medications like cimetidine or ranitidine work through this mechanism to reduce acid production.
D. Sucralfate creates a viscous, protective barrier that adheres to the ulcer site, shielding it from further damage by gastric acid, bile, and pepsin for up to 6 hours, thereby promoting healing.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. 4 teaspoons – This is incorrect because 4 teaspoons would provide 400 mg (100 mg x 4 = 400 mg), but the correct dose per administration is 400 mg. However, this is not the correct calculation, as only 2 teaspoons are needed.
B. 2 teaspoons – This is correct. The prescribed dose is 400 mg, and since the medication concentration is 100 mg per teaspoon, 2 teaspoons (100 mg x 2 = 200 mg) is the correct dose for each administration.
C. 1 teaspoon – This is incorrect because 1 teaspoon would only provide 100 mg, and the prescribed dose is 400 mg. This is not enough to meet the prescribed dose.
D. 3 teaspoons – This is incorrect because 3 teaspoons would provide 300 mg (100 mg x 3 = 300 mg), which is not enough to meet the prescribed 400 mg dose.
Correct Answer is ["B","D"]
Explanation
A. Restlessness is not a common side effect of cimetidine. Neurological side effects typically involve sedation or confusion rather than hyperactivity.
B. Lethargy is a potential adverse effect of cimetidine, especially in older adults or those with renal dysfunction, due to the drug’s impact on the central nervous system.
C. Increased libido is not associated with cimetidine. In fact, it may cause decreased libido and sexual dysfunction in some cases.
D. Confusion is a known complication of cimetidine, particularly in elderly clients with impaired renal function, as the drug can accumulate in the body and affect the brain.
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