Which of the following risk factors is associated with a client having a higher risk of experiencing status asthmaticus?

Choice A Reason:

Genetics is correct. There is evidence to suggest that genetics play a role in the development of multiple sclerosis. Although no single gene has been identified as the cause of MS, certain genetic variations have been associated with an increased risk of developing the disease. Having a first-degree relative with MS increases an individual's risk, although the overall genetic contribution to MS susceptibility is thought to be relatively modest.

Choice B Reason:

Environmental factors is correct. Environmental factors are believed to play a significant role in the development of multiple sclerosis, particularly in individuals with a genetic predisposition. Factors such as vitamin D deficiency, smoking, exposure to certain infections (such as Epstein-Barr virus), and geographic location (latitude) have been implicated as potential triggers for MS development.

Choice C Reason:

Upper respiratory infections is incorrect. While infections may trigger exacerbations or relapses in individuals with existing multiple sclerosis, there is limited evidence to suggest that upper respiratory infections contribute directly to the development of MS. However, some research suggests that viral infections, particularly those occurring during childhood or adolescence, may influence the risk of developing MS later in life.

Choice D Reason:

Autoimmune factors is correct. Multiple sclerosis is widely recognized as an autoimmune disease, characterized by immune-mediated inflammation and damage to the central nervous system. In MS, the immune system mistakenly attacks myelin, the protective covering of nerve fibers, leading to demyelination and neurological dysfunction. Autoimmune factors are therefore considered central to the pathogenesis of MS.

Choice E Reason:

Urinary tract infections is incorrect. While urinary tract infections (UTIs) are common in individuals with multiple sclerosis due to bladder dysfunction associated with the disease, there is no direct evidence to suggest that UTIs contribute to the development of MS.

Choice A Reason:

Glatiramer acetate is incorrect because it is used in the treatment of multiple sclerosis (MS) to reduce the frequency of relapses and delay disease progression. It is not indicated for spasm-induced incontinence.

Choice B Reason:

Dulaglutide is incorrect because it is a medication used to treat type 2 diabetes by improving blood sugar control. It is not indicated for the treatment of spasm-induced incontinence.

Choice C Reason:

Montelukast sodium is incorrect because it is a leukotriene receptor antagonist primarily used to manage asthma and allergic rhinitis. It is not indicated for the treatment of spasm-induced incontinence.

Choice D Reason:

Oxybutynin is an anticholinergic medication commonly used to treat overactive bladder and urinary incontinence, including spasm-induced incontinence that can occur in individuals with spinal cord injury. It works by relaxing the smooth muscles of the bladder, thereby reducing involuntary contractions that contribute to urinary urgency and incontinence.