A patient is taking an inducer medication. The provider added a new medication. What is the effect of the inducer medication on the newly added medication?
Increases the blood level of the newly added medication.
Decreases the blood level of the newly added medication.
Increases the half-life of the newly added medication.
Doesn’t have any effect on new medications.
The Correct Answer is B
Choice A Reason:
Inducer medications do not increase the blood level of newly added medications. Instead, they enhance the activity of enzymes that metabolize drugs, leading to a faster breakdown and lower concentration of the new medication in the bloodstream. This can result in reduced efficacy of the newly added medication.
Choice B Reason:
Inducer medications increase the activity of enzymes, particularly those in the cytochrome P450 family, which are responsible for drug metabolism. This increased enzyme activity accelerates the breakdown of the newly added medication, thereby decreasing its blood level and potentially reducing its therapeutic effect. For example, rifampin is a well-known inducer that can significantly lower the levels of drugs metabolized by CYP3A4.
Choice C Reason:
Inducer medications do not increase the half-life of newly added medications. On the contrary, by enhancing the metabolic activity of enzymes, they typically reduce the half-life of the new medication. This means the drug is broken down and eliminated from the body more quickly.
Choice D Reason:
Inducer medications do have a significant effect on new medications. They alter the metabolism of drugs by increasing the activity of metabolic enzymes, which can lead to decreased blood levels and reduced effectiveness of the new medication. Ignoring this interaction can result in subtherapeutic drug levels and treatment failure.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A: Convert Amino Acid to Glucose
The process of converting amino acids to glucose is known as gluconeogenesis. This metabolic pathway allows the body to produce glucose from non-carbohydrate sources, such as amino acids, during periods of fasting or intense exercise. While this process is crucial for maintaining blood glucose levels, it is not the definition of glycogenolysis.
Choice B: Break Down Glycogen to Glucose
Glycogenolysis is the biochemical process of breaking down glycogen into glucose. Glycogen, a stored form of glucose in the liver and muscle cells, is broken down to provide immediate energy and to maintain blood glucose levels during fasting or intense physical activity. This process is regulated by hormones such as glucagon and epinephrine, which activate enzymes that catalyze the breakdown of glycogen into glucose-1-phosphate and then into glucose-6-phosphate3. The glucose-6-phosphate can then be used in glycolysis to produce energy or released into the bloodstream to maintain blood glucose levels.
Choice C: Convert Glucose to Amino Acid
The conversion of glucose to amino acids is not a typical metabolic pathway. Instead, glucose is primarily used for energy production through glycolysis and the citric acid cycle. Amino acids are synthesized from intermediates of these pathways and other metabolic processes, but glucose itself is not directly converted into amino acids.
Choice D: Convert Fat to Amino Acid
The conversion of fats to amino acids is not a standard metabolic process. Fats are broken down into fatty acids and glycerol through lipolysis. Fatty acids can be further oxidized to produce energy, while glycerol can enter gluconeogenesis to produce glucose. Amino acids, on the other hand, are derived from dietary proteins or synthesized from other amino acids and metabolic intermediates.
Correct Answer is ["A","C"]
Explanation
Choice A Reason:
Acidosis is indicated by a pH lower than the normal range of 7.35-7.45. In this case, the patient’s pH is 7.3, which confirms acidosis. Acidosis can be caused by either respiratory or metabolic factors, but the low pH alone confirms the presence of acidosis.
Choice B Reason:
Compensation refers to the body’s attempt to return the pH to normal by adjusting the levels of CO2 or HCO3-. In this case, the HCO3- level is within the normal range (22-26 mEq/L), indicating that there is no metabolic compensation occurring. Therefore, this choice is incorrect.
Choice C Reason:
Respiratory acidosis is indicated by an elevated PaCO2 level, which is higher than the normal range of 36-44 mmHg. The patient’s PaCO2 is 48 mmHg, suggesting that the acidosis is due to respiratory factors. This is consistent with the patient’s history of smoking and symptoms of respiratory distress.
Choice D Reason:
Alkalosis is indicated by a pH higher than the normal range of 7.35-7.45. Since the patient’s pH is 7.3, which is below the normal range, this indicates acidosis, not alkalosis. Therefore, this choice is incorrect.
Choice E Reason:
Metabolic acidosis is indicated by a low HCO3- level. In this case, the patient’s HCO3- level is within the normal range (25 mEq/L), indicating that the acidosis is not metabolic. Therefore, this choice is incorrect.
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