Which term means moving of the medication from the site of administration to the target organ?

A. "Break the lozenge in half, making it easier to swallow."
Breaking the lozenge in half may reduce the effectiveness by altering how the medication is released and absorbed. Lozenge medications are designed to dissolve slowly.

B. "Take the lozenge with a glass of milk."
Milk could coat the mouth and throat, potentially reducing the absorption of the medication and decreasing its effectiveness.

C. "Swallow the medication with a drink of water."
Swallowing the lozenge whole would bypass the intended local effect in the mouth and throat, reducing the medication’s effectiveness in treating a sore throat.

D. "Suck on the lozenge until it dissolves." Sucking on the lozenge until it dissolves allows the medication to be released slowly and absorbed directly into the tissues of the mouth and throat, where it can have the most therapeutic effect.

A. Biotransformation: This refers to the chemical alteration of a drug in the body, usually by the liver, into metabolites. It does not describe the movement of the drug to the target organ.

B. Distribution: This is the correct answer. Distribution refers to the process by which a drug is transported by the blood to the target organ or tissues after it is absorbed into the bloodstream.

C. Excretion: This is the process of eliminating waste products, including drugs, from the body, typically through the kidneys. It does not involve the movement to the target organ.

D. Absorption: This refers to the process by which a drug enters the bloodstream from the site of administration. It precedes distribution but does not describe the movement to the target organ.