A client with Osteosarcoma asks the nurse about the pathophysiology of the disease.
Which response by the nurse is accurate?
"Osteosarcoma arises from mature bone-forming cells called osteocytes.”
"Genetic mutations leading to uncontrolled proliferation of osteoblasts contribute to Osteosarcoma.”
"Osteosarcoma typically starts in the epiphyseal region of long bones.”
"The tumor primarily extends into the muscle tissues surrounding the bone.”
The Correct Answer is B
Choice A rationale:
Osteosarcoma arises from mature bone-forming cells called osteocytes.
Rationale: This statement is not accurate.
Osteosarcoma does not originate from osteocytes.
Instead, it arises from osteoblasts, which are immature bone-forming cells.
Genetic mutations can lead to uncontrolled proliferation of osteoblasts, contributing to the development of Osteosarcoma.
Choice B rationale:
Genetic mutations leading to uncontrolled proliferation of osteoblasts contribute to Osteosarcoma.
Rationale: This statement is accurate.
Osteosarcoma is characterized by genetic mutations that cause osteoblasts to multiply uncontrollably, resulting in the formation of malignant bone tumors.
This is a key aspect of the disease's pathophysiology.
Choice C rationale:
Osteosarcoma typically starts in the epiphyseal region of long bones.
Rationale: This statement is not accurate.
Osteosarcoma usually begins in the metaphyseal region of long bones, not the epiphyseal region.
The metaphysis is the area of the bone where growth occurs, making it more susceptible to malignant changes.
Choice D rationale:
The tumor primarily extends into the muscle tissues surrounding the bone.
Rationale: This statement is not accurate.
Osteosarcoma primarily affects the bone itself, with the tumor originating within the bone tissue.
While it can extend into nearby soft tissues, such as muscles, it does not primarily start in muscle tissues.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
"Removing all cancer cells without surgery." Surgical treatment is a primary approach in managing Osteosarcoma.
The goal of surgery is not to remove cancer cells without surgery but to remove the tumor and surrounding affected tissues while preserving the affected limb whenever possible.
Complete removal of all cancer cells is challenging with surgery alone, which is why other treatments like chemotherapy are often used in conjunction.
Choice C rationale:
"Administering radiation therapy only." While radiation therapy may be used as part of the treatment plan for Osteosarcoma, it is not the primary goal of surgical treatment.
Surgical intervention, such as limb-sparing surgery or amputation, is the mainstay of therapy for Osteosarcoma.
Choice D rationale:
"Performing amputation as the primary treatment." While amputation may be necessary in some cases of Osteosarcoma, the primary goal of surgical treatment is to preserve the affected limb whenever possible.
Amputation is considered when limb preservation is not feasible or when the tumor is very large and invasive.
Correct Answer is ["A","C","D"]
Explanation
"Examine the patient's liver function." While monitoring liver function is important in cancer patients, it is not a specific assessment related to Osteosarcoma.
Osteosarcoma primarily affects the bones and may spread to the lungs or other distant sites rather than the liver.
Choice E rationale:
"Perform a neurological examination." A neurological examination is not a standard assessment for Osteosarcoma.
This cancer primarily involves the bones and surrounding tissues, and neurological symptoms are not typically associated with it.
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