A nurse is caring for a client who consumed alcohol 2 days after taking disulfiram. The nurse should monitor the client for which of the following findings?
Constipation
Dry skin
Hypotension
Urinary retention
The Correct Answer is C
Choice A reason: Constipation isn’t a primary effect of disulfiram-alcohol reaction, which causes acetaldehyde buildup, triggering vasodilation and nausea, not gut motility issues. Scientifically, this reaction targets cardiovascular and systemic responses, lacking evidence for significant gastrointestinal stasis as a monitored outcome in this scenario.
Choice B reason: Dry skin isn’t linked to disulfiram-alcohol interaction, which induces flushing and sweating from acetaldehyde toxicity, not dehydration. Scientifically, the reaction affects vascular and autonomic systems, producing moist, not dry, skin responses, making this an unrelated finding for monitoring here.
Choice C reason: Hypotension occurs in disulfiram-alcohol reaction as acetaldehyde dilates vessels, dropping blood pressure. This cardiovascular effect, alongside tachycardia, is a key sign to monitor, aligning with scientific understanding of the drug’s inhibition of aldehyde dehydrogenase, causing systemic distress.
Choice D reason: Urinary retention isn’t a typical disulfiram-alcohol effect; the reaction focuses on vasodilation, nausea, and hypotension from acetaldehyde. Scientifically, autonomic overstimulation may occur, but bladder dysfunction isn’t a primary outcome, making this less critical to monitor than cardiovascular collapse.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Swallowing isn’t an option for chewable isosorbide; it’s designed for sublingual absorption. This advice is incorrect and won’t address vasodilatory headache effects.
Choice B reason: Discontinuing isosorbide risks angina exacerbation in cardiac patients. Headaches are tolerable side effects, so stopping isn’t advised without provider input.
Choice C reason: Empty stomach intake doesn’t reduce isosorbide’s vasodilatory headaches. Timing doesn’t alter its nitrate-induced vessel dilation, making this ineffective advice.
Choice D reason: Headaches from isosorbide’s vasodilation typically subside with tolerance over time. This reassures the client, aligning with expected nitrate therapy adaptation.
Correct Answer is B
Explanation
Choice A reason: Calcium-fortified juice binds doxycycline, reducing absorption via chelation in the gut. Scientifically, tetracyclines like doxycycline lose efficacy with divalent cations, worsening nausea without treating chlamydia, making this counterproductive to therapeutic goals and pharmacokinetics.
Choice B reason: Taking doxycycline with crackers minimizes gastric irritation, reducing nausea while maintaining absorption. Scientifically, light food buffers the stomach without significantly impairing tetracycline bioavailability, aligning with evidence-based advice to improve tolerability and adherence in chlamydia treatment.
Choice C reason: Lying down after doxycycline risks esophageal irritation or reflux, worsening nausea. Scientifically, upright posture post-dose prevents drug stasis, which can cause ulcers, making this contrary to safe administration practices for tetracyclines per clinical guidelines.
Choice D reason: Antacids with magnesium or aluminum bind doxycycline, decreasing absorption and efficacy. Scientifically, this interaction undermines chlamydia treatment, as tetracyclines require an acidic environment for uptake, rendering this incompatible with therapeutic success and worsening outcomes.
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