A nurse is discussing the underlying genetic defect in cystic fibrosis (CF) with a client. Which of the following statements accurately describes the primary genetic abnormality in CF?

"CF is caused by an extra chromosome, leading to genetic imbalance."

"In CF, there is a duplication of the CFTR gene on chromosome 7."

"CF results from a mutation in the CFTR gene, which codes for a dysfunctional chloride channel."

"CF is characterized by the absence of the CFTR gene in affected individuals."

Answer and Explanation

The Correct Answer is C

A) Incorrect. CF is not caused by an extra chromosome; it is a genetic disorder resulting from mutations in specific genes.

B) Incorrect. CF is not characterized by a duplication of the CFTR gene but rather by various mutations in this gene.

C) Correct. CF is primarily caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene, leading to the production of dysfunctional chloride channels.

D) Incorrect. CF is not characterized by the absence of the CFTR gene; instead, it involves various mutations in this gene.

Nursing Test Bank

Quiz #1: RN Exams Pharmacology Exams Quiz #2: RN Exams Medical-Surgical Exams Quiz #3: RN Exams Fundamentals Exams Quiz #4: RN Exams Maternal-Newborn Exams Quiz #5: RN Exams Anatomy and Physiology Exams Quiz #6: RN Exams Obstetrics and Pediatrics Exams Quiz #7: RN Exams Fluid and Electrolytes Exams Quiz #8: RN Exams Community Health Exams Quiz #9: RN Exams Promoting Health across the lifespan Exams Quiz #10: RN Exams Multidimensional care Exams

Get 100+ Naxlex Exit Exams for $79 Try Naxlex NCLEX-RN (14 Day Free-Trial)

Naxlex Comprehensive Predictor Exams

Quiz #1: Naxlex RN Comprehensive online practice 2019 B with NGN Quiz #2: Naxlex RN Comprehensive Predictor 2023 Quiz #3: Naxlex RN Comprehensive Predictor 2023 Exit Exam A Quiz #4: Naxlex HESI Exit LPN Exam Quiz #5: Naxlex PN Comprehensive Predictor PN 2020 Quiz #6: Naxlex VATI PN Comprehensive Predictor 2020 Quiz #8: Naxlex PN Comprehensive Predictor 2023 - Exam 1 Quiz #10: Naxlex HESI PN Exit exam Quiz #11: Naxlex HESI PN EXIT Exam 2

Free Nursing Study Resources

Correct Answer is C

Explanation

A) Incorrect. Meconium ileus is a complication typically seen in newborns with CF, not in adults.

B) Incorrect. Failure to thrive is a concern in infants and young children with CF but not typically in adults.

C) Correct. Osteoporosis is a common complication in adults with CF due to malabsorption of calcium and vitamin D, chronic inflammation, and reduced physical activity.

D) Incorrect. Rapid growth and development are typically observed in adolescents, not as a complication but as a part of normal growth.

A. Sweat chloride test B. Chest X-ray C. Pulmonary function test D. Complete blood count (CBC)

Correct Answer is A

Explanation

A) Correct. The sweat chloride test is commonly used for newborn screening for CF. Elevated sweat chloride levels are indicative of CF.

B) Incorrect. Chest X-rays may be used to assess lung changes in individuals with CF but are not a primary diagnostic test, especially in newborns.

C) Incorrect. Pulmonary function tests are used to evaluate lung function but are not typically performed as part of newborn screening for CF.

D) Incorrect. A complete blood count (CBC) is a general blood test and is not specific for CF diagnosis.

View Question and Answer

Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.

Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today

A nurse is discussing the underlying genetic defect in cystic fibrosis (CF) with a client. Which of the following statements accurately describes the primary genetic abnormality in CF?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is educating a client with cystic fibrosis (CF) about potential complications of the disease. Which of the following should the nurse mention as a common complication of CF in adults?

Correct Answer is C

Explanation

A nurse is educating a client about the diagnostic evaluation of cystic fibrosis (CF). What test is commonly used to screen for CF in newborns shortly after birth?

Correct Answer is A

Explanation

A nurse is educating a client about the inheritance pattern of cystic fibrosis (CF). What information should the nurse provide regarding the likelihood of a child developing CF if both parents are carriers?

A nurse is educating a client with cystic fibrosis (CF) about airway clearance techniques. Which of the following airway clearance methods involves the use of a mechanical device to deliver high-frequency chest wall oscillations?

A client with cystic fibrosis (CF) presents with clubbed fingers during a routine examination. What should the nurse explain to the client regarding the significance of clubbing in CF?

A nurse is providing discharge instructions to the parents of a child with cystic fibrosis. Which statement by the parents indicates a need for further education?

A nurse is caring for a child with cystic fibrosis (CF). What gastrointestinal symptom commonly observed in CF should the nurse be vigilant for?

A nurse is discussing nutritional management with a client who has cystic fibrosis (CF). What dietary recommendation should the nurse emphasize to optimize nutritional intake in individuals with CF?

A nurse is discussing the role of the cystic fibrosis transmembrane conductance regulator (CFTR) protein with a patient. What is the primary function of the CFTR protein in normal physiology?

A nurse is explaining the typical clinical manifestations of cystic fibrosis (CF) to a newly diagnosed adolescent client. Which symptom should the nurse emphasize as a hallmark of CF?