A nurse is discussing the underlying genetic defect in cystic fibrosis (CF) with a client. Which of the following statements accurately describes the primary genetic abnormality in CF?
"CF is caused by an extra chromosome, leading to genetic imbalance."
"In CF, there is a duplication of the CFTR gene on chromosome 7."
"CF results from a mutation in the CFTR gene, which codes for a dysfunctional chloride channel."
"CF is characterized by the absence of the CFTR gene in affected individuals."
The Correct Answer is C
A) Incorrect. CF is not caused by an extra chromosome; it is a genetic disorder resulting from mutations in specific genes.
B) Incorrect. CF is not characterized by a duplication of the CFTR gene but rather by various mutations in this gene.
C) Correct. CF is primarily caused by mutations in the CFTR (cystic fibrosis transmembrane conductance regulator) gene, leading to the production of dysfunctional chloride channels.
D) Incorrect. CF is not characterized by the absence of the CFTR gene; instead, it involves various mutations in this gene.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A) Incorrect. Frequent nosebleeds are not common gastrointestinal symptoms in CF.
B) Correct. Abdominal pain and bloating are common gastrointestinal symptoms in CF, often due to the impact of thickened mucus on the pancreas and intestines.
C) Incorrect. Rapid weight gain is not a typical gastrointestinal symptom in CF; individuals with CF often struggle with poor weight gain and malnutrition.
D) Incorrect. Muscle weakness is not a common gastrointestinal symptom in CF but may be associated with other complications.
Correct Answer is C
Explanation
A) Incorrect. While coughing is important, huff coughing is a more effective and less strenuous airway clearance technique for CF patients.
B) Incorrect. Controlled breathing exercises may help with relaxation but are not the primary airway clearance technique.
C) Correct. Huff coughing is a technique where the client takes a deep breath and forcefully exhales in short bursts, helping to move mucus from the airways.
D) Incorrect. Vigorous exercise is beneficial for CF patients but should not replace specific airway clearance techniques.
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