A nurse is educating a client about a new prescription for celecoxib.
Which of the following information should the nurse include in the teaching about the medication's mechanism of action?
Inhibits histamine response.
Inhibits COX-2.
Inhibits COX-1.
Inhibits beta receptors.
The Correct Answer is B
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Propylthiouracil (PTU) is used to treat hyperthyroidism. It works by inhibiting the production of thyroid hormones, thereby reducing symptoms of hyperthyroidism such as rapid heart rate, sweating, and nervousness.
Choice B rationale
Propylthiouracil (PTU) is not used to treat hyperglycemia. Medications for hyperglycemia include insulin and oral hypoglycemic agents.
Choice C rationale
Propylthiouracil (PTU) is not indicated for hypoglycemia. Treatment for hypoglycemia typically includes glucose administration or glucagon.
Choice D rationale
Propylthiouracil (PTU) is not used to treat hypothyroidism. Hypothyroidism is treated with thyroid hormone replacement therapy, such as levothyroxine.
Correct Answer is {"dropdown-group-1":"C"}
Explanation
Choice A rationale: Furosemide is a loop diuretic used to reduce fluid overload in CHF patients. However, it can exacerbate electrolyte imbalances, particularly hypokalemia. Since the client is already experiencing muscle spasms and has low calcium levels, additional diuretic therapy could worsen these symptoms.
Choice B rationale: Metoprolol is a beta-blocker used to manage hypertension and heart rate in CHF patients. While beneficial for blood pressure control, it does not address the immediate issue of muscle spasms and constipation the client is experiencing.
Choice C rationale: Potassium chloride is indicated to address potential hypokalemia, which may be causing the client's muscle spasms. CHF patients on diuretics often experience low potassium levels, so supplementation is crucial to prevent complications and alleviate symptoms.
Choice D rationale: Acetaminophen is an analgesic and antipyretic, useful for pain and fever management. However, it does not address the client's reported muscle spasms, which are likely related to electrolyte imbalances.
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