A nurse is educating a client about a new prescription for celecoxib.
Which of the following information should the nurse include in the teaching about the medication's mechanism of action?
Inhibits histamine response.
Inhibits COX-2.
Inhibits COX-1.
Inhibits beta receptors.
The Correct Answer is B
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Dextromethorphan is not used for asthma. Asthma treatment typically involves bronchodilators and anti-inflammatory medications.
Choice B rationale
Dextromethorphan is an antitussive used to suppress coughing. It acts on the cough center in the brain to reduce the urge to cough.
Choice C rationale
This medication is not used for pain reduction. Pain management usually involves analgesics or anti-inflammatory drugs.
Choice D rationale
Dextromethorphan is not indicated for allergic rhinitis. Allergic rhinitis treatments typically include antihistamines or nasal corticosteroids.
Correct Answer is A
Explanation
Choice A rationale
Rotating injection sites helps prevent lipohypertrophy, which is the thickening of subcutaneous tissue due to repeated insulin injections at the same site.
Choice B rationale
Performing injections at the same location every time increases the risk of lipohypertrophy, leading to poor insulin absorption and erratic glucose control.
Choice C rationale
Administering an additional dose of insulin as needed does not address the issue of lipohypertrophy and can lead to hypoglycemia if not carefully monitored.
Choice D rationale
Insulin is a peptide hormone that must be injected. Taking it orally is ineffective as it would be broken down in the digestive system.
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