A nurse is educating a client about a new prescription for celecoxib.
Which of the following information should the nurse include in the teaching about the medication's mechanism of action?
Inhibits histamine response.
Inhibits COX-2.
Inhibits COX-1.
Inhibits beta receptors.
The Correct Answer is B
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A rationale
Aspirin is a first-generation NSAID that reduces inflammation and pain. It works by inhibiting the enzyme cyclooxygenase, which results in decreased production of prostaglandins.
Choice B rationale
Dimenhydrinate is an antihistamine used to prevent and treat nausea, vomiting, and dizziness caused by motion sickness. It is not considered an NSAID.
Choice C rationale
Cetirizine is an antihistamine used to relieve allergy symptoms. It is not considered an NSAID.
Choice D rationale
Celecoxib is a second-generation NSAID that selectively inhibits cyclooxygenase-2 (COX-2). It is not a first-generation NSAID.
Correct Answer is ["B","C"]
Explanation
Choice A rationale
Furosemide is a loop diuretic that inhibits the sodium-potassium-chloride co-transporter in the thick ascending limb of the loop of Henle. This results in significant loss of potassium in the urine.
Choice B rationale
NaoxGhe is not a recognized diuretic or medication and should not be included in any in-service discussion.
Choice C rationale
Spironolactone is a potassium-sparing diuretic that works by antagonizing the effects of aldosterone in the distal tubules, reducing potassium excretion.
Choice D rationale
"None of the above" is not a medication but rather a non-relevant option in this context.
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