A nurse is educating a client about a new prescription for celecoxib.
Which of the following information should the nurse include in the teaching about the medication's mechanism of action?
Inhibits histamine response.
Inhibits COX-2.
Inhibits COX-1.
Inhibits beta receptors.
The Correct Answer is B
Choice A rationale
Celecoxib does not inhibit the histamine response. Histamine is involved in allergic reactions, and celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that targets specific enzymes involved in inflammation.
Choice B rationale
Celecoxib specifically inhibits COX-2, an enzyme involved in the inflammation pathway. This selective inhibition helps reduce inflammation and pain without significantly affecting COX-1, which is protective for the stomach lining.
Choice C rationale
COX-1 is not the primary target of celecoxib. Inhibition of COX-1 can lead to gastrointestinal side effects, which celecoxib aims to minimize by selectively inhibiting COX-2 instead.
Choice D rationale
Celecoxib does not inhibit beta receptors. Beta receptors are involved in cardiovascular responses, and beta blockers are used for conditions like hypertension, not inflammation.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A rationale
Glucagon (GlucaGen) is not used for hyperglycemia. Hyperglycemia requires insulin or oral hypoglycemic agents to lower blood glucose levels.
Choice B rationale
Glucagon (GlucaGen) is used to treat hypoglycemia, especially in emergency situations when a person is unconscious or unable to consume oral glucose. It raises blood glucose levels by stimulating the liver to release stored glucose into the bloodstream.
Choice C rationale
Glucagon (GlucaGen) is not used for the treatment of type 2 diabetes mellitus. Management of type 2 diabetes typically includes lifestyle changes, oral hypoglycemic agents, and sometimes insulin therapy.
Choice D rationale
Glucagon (GlucaGen) is not used for diabetes insipidus. Diabetes insipidus is treated with medications such as desmopressin, which helps reduce urine output. .
Correct Answer is B
Explanation
Choice B rationale
Sucralfate (Carafate) acts by forming a viscous, adhesive substance that binds to the ulcer site, creating a physical barrier protecting it from stomach acid and allowing healing.
Choice A rationale
Sucralfate does not function as an endogenous prostaglandin; it does not mimic or enhance prostaglandin activity in the GI tract.
Choice C rationale
Sucralfate does not neutralize gastric acid; that is the function of antacids.
Choice D rationale
Sucralfate does not antagonize H2 receptors on parietal cells; H2 receptor antagonists are a different class of medication.
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