A nurse is providing an in-service for hydrochlorothiazide (Hydro Diuril). Which of the following statements are TRUE regarding hydrochlorothiazide? (Select All That Apply).

The medication works in the distal tubule to block the reabsorption of sodium and chloride,

This medication is the first choice to treat essential hypertension

A complication of this medication is urinary retention

A complication of this medication is opioid toxicity

Answer and Explanation

Correct Answer : A,B

A.   Hydrochlorothiazide is a thiazide diuretic that works in the distal convoluted tubule of the kidney. It inhibits the reabsorption of sodium and chloride, leading to increased excretion of water, sodium, and chloride.
B.   Hydrochlorothiazide is often the first-line treatment for hypertension because it helps reduce blood pressure through diuresis (increased urine output), which reduces fluid volume in the body.
C.   Urinary retention is not a known complication of hydrochlorothiazide. Instead, it may cause frequent urination due to its diuretic effect.
D.   Hydrochlorothiazide does not interact with opioids in a way that would cause opioid toxicity. It primarily affects sodium and water balance in the body.

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Correct Answer is D

Explanation

A. Hydrochlorothiazide does not typically cause increased swelling of the ankles. It is a diuretic and helps reduce fluid retention.
B. Fluid intake should not be restricted unless specifically indicated. Diuretics like hydrochlorothiazide increase urine output, and adequate fluid intake is generally encouraged to prevent dehydration.
C. Taking hydrochlorothiazide at bedtime is not recommended due to the increased urination, which may disrupt sleep.
D. Taking this medication with food can help prevent gastrointestinal upset, which is a common side effect of hydrochlorothiazide.

A. Blood potassium 3.9 mEq/L B. Urine output 500 ml in 5 hours C. Blood potassium 8 mEq D. Urine output 200 mL in 4 hours

Correct Answer is C

Explanation

A. A blood potassium level of 3.9 mEq/L is normal and does not require intervention.
B. Urine output of 500 mL in 5 hours is not concerning and is within the expected range.
C. A blood potassium level of 8 mEq/L is dangerously high, indicating hyperkalemia, which can lead to life-threatening arrhythmias.
D. Urine output of 200 mL in 4 hours could be a concern for dehydration or renal issues, but it is not directly related to spironolactone use.

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A nurse is providing an in-service for hydrochlorothiazide (Hydro Diuril). Which of the following statements are TRUE regarding hydrochlorothiazide? (Select All That Apply).

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A nurse is providing information to a client who has a new prescription for hydrochlorothiazide (Hydro Diuril). Which of the following information should the nurse include?

Correct Answer is D

Explanation

A nurse is monitoring a client who is receiving spironolactone (Aldactone). Which of the following findings should the nurse report to the provider?

Correct Answer is C

Explanation

A client has been newly diagnosed with breast cancer. The client has been prescribed ondansetron (Zofran), but the client is unsure of the indication for this medication. What is your response as a nurse?

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