A nurse prepares to administer vancomycin 15 mg/kg/day divided equally every 12 hr. The client weighs 198 lb. How many mg should the nurse administer with each dose? (Round the answer to the nearest whole number. Use a leading zero if it applies. Do not use a trailing zero.)
The Correct Answer is ["675"]
To calculate the dosage of vancomycin, we first convert the client's weight from pounds to kilograms, knowing that 1 kilogram is approximately 2.2 pounds. The client weighs 198 pounds, which is equivalent to about 90 kilograms (198 lb / 2.2). The prescribed dose is 15 mg/kg/day, so for a 90 kg individual, this would be 1350 mg/day (15 mg/kg * 90 kg). Since the dose is divided equally every 12 hours, the nurse would administer half of the daily dose every 12 hours, resulting in 675 mg per dose (1350 mg/day / 2). Therefore, the nurse should administer 675 mg of vancomycin with each dose.
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Correct Answer is {"A":{"answers":"C"},"B":{"answers":"A"},"C":{"answers":"B"},"D":{"answers":"D"}}
Explanation
Warfarin: Vitamin K is the primary reversal agent for anticoagulation with warfarin. It helps restore normal clotting factor production in the liver.
Heparin: Protamine sulfate is the specific reversal agent for heparin, neutralizing its anticoagulant effects.
Rivaroxaban: Andexanet alfa is a specific reversal agent for rivaroxaban and other Factor Xa inhibitors, reversing their anticoagulant effects.
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Correct Answer is D
Explanation
A. Increased creatinine clearance is not a common effect of gemfibrozil; rather, it may lead to liver function changes or muscle-related side effects.
B. Gemfibrozil does not typically decrease prothrombin time (PT); this option does not relate to its mechanism of action.
C. Hyperkalemia is not a typical side effect of gemfibrozil; it may be more relevant to other medications, particularly those affecting the kidneys.
D. Gallstones are a known side effect of gemfibrozil, as the drug can increase biliary cholesterol saturation, leading to the formation of stones.
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