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The nurse is caring for a client who currently has a deep vein thrombosis. Which of the following medications would be administered to lyse existing clots? (Select All that Apply.)

Aspirin

Low-molecular weight Heparin

Heparin

alteplase (Activase)

warfarin (Coumadin)

anistreplase (Eminase)

Answer and Explanation

Correct Answer : D,F

A. Aspirin is an antiplatelet medication that prevents new clots but does not actively lyse existing clots.

B. Low-molecular weight heparin is primarily used for preventing clot formation rather than lysing existing clots.

C. Heparin prevents further clot formation but does not dissolve existing clots.

D. Alteplase (Activase) is a thrombolytic agent specifically indicated for the dissolution of existing clots in acute situations like deep vein thrombosis.

E. Warfarin is an anticoagulant that prevents clotting but does not directly lyse clots; it is used for long-term management.

F. Anistreplase (Eminase) is another thrombolytic agent used to lyse existing clots and is indicated in similar situations.

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Correct Answer is {"A":{"answers":"C"},"B":{"answers":"A"},"C":{"answers":"B"},"D":{"answers":"D"}}

Explanation

Warfarin: Vitamin K is the primary reversal agent for anticoagulation with warfarin. It helps restore normal clotting factor production in the liver.

Heparin: Protamine sulfate is the specific reversal agent for heparin, neutralizing its anticoagulant effects.

Rivaroxaban: Andexanet alfa is a specific reversal agent for rivaroxaban and other Factor Xa inhibitors, reversing their anticoagulant effects.

Beta Blockers: While there is no specific reversal agent, glucagon can help increase heart rate and myocardial contractility in cases of beta-blocker overdose.

A. "Depending on the level of your PT/INR, the clot will begin to dissolve." B. "Heparin goes not dissolve clots. It stops new clots from forming" C. "It usually takes heparin at least 2 to 3 days to reach a therapeutic blood level." D. "After the first dose, the clot will begin to dissolve."

Correct Answer is B

Explanation

A. PT/INR is more relevant for monitoring anticoagulant therapy like warfarin, not heparin.

B. This response is accurate; heparin prevents further clot formation but does not dissolve existing clots, which can take time for the body to reabsorb.

C. Heparin begins to exert its effects quickly, and therapeutic levels are not measured by PT/INR but by aPTT or anti-factor Xa levels.

D. Clots do not dissolve immediately after the first dose of heparin; the medication's role is to prevent clot extension.

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The nurse is caring for a client who currently has a deep vein thrombosis. Which of the following medications would be administered to lyse existing clots? (Select All that Apply.)

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Naxlex Comprehensive Predictor Exams

A charge nurse is teaching a group of nurses about the antagonist action of reversal medications. For each medication listed below, click to specify the expected reversal agent.

Correct Answer is {"A":{"answers":"C"},"B":{"answers":"A"},"C":{"answers":"B"},"D":{"answers":"D"}}

Explanation

A nurse is caring for a client who is diagnosed with a deep vein thrombosis (DVT) and is receiving heparin. The client asks the nurse how long it will take for the heparin to dissolve the clot, which of the following responses should the nurse give?

Correct Answer is B

Explanation

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