A nurse teaches a patient who takes daily low-dose aspirin for protection against myocardial infarction and stroke to avoid also taking which medication?

Diphenhydramine [Benadryl]

Loratadine [Claritin]

Ibuprofen [Motrin]

Multivitamin

Answer and Explanation

The Correct Answer is C

Choice A reason: Diphenhydramine, an antihistamine, does not significantly interact with aspirin’s antiplatelet effects. It primarily blocks histamine receptors, affecting allergies, not platelet aggregation. While it may cause drowsiness, it doesn’t increase bleeding risk or counteract aspirin’s cardiovascular benefits, making it safe to use concurrently with low-dose aspirin.

Choice B reason: Loratadine, a second-generation antihistamine, targets histamine receptors to relieve allergy symptoms. It has no known interaction with aspirin’s antiplatelet mechanism or bleeding risk. Its minimal side effect profile makes it compatible with low-dose aspirin for cardiovascular protection, so avoiding it is unnecessary in this context.

Choice C reason: Ibuprofen, an NSAID, competes with aspirin for COX-1 binding sites, reducing aspirin’s antiplatelet effect critical for preventing myocardial infarction and stroke. It also increases gastrointestinal bleeding risk when combined with aspirin, making it contraindicated for patients on low-dose aspirin therapy, thus the correct choice to avoid.

Choice D reason: Multivitamins do not interfere with aspirin’s antiplatelet action or increase bleeding risk. They provide supplemental nutrients without affecting COX-1 inhibition or platelet aggregation. There’s no pharmacological basis for avoiding multivitamins with low-dose aspirin, making this choice irrelevant for the patient’s cardiovascular regimen.

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Correct Answer is D

Explanation

Choice A reason: Pulse oximetry of 95% is near normal and not a major concern for beta agonist administration. Tachycardia is more critical due to cardiac stimulation, so this is incorrect.

Choice B reason: A respiratory rate of 22 is slightly elevated but acceptable in respiratory conditions. Beta agonists target airways, but tachycardia is a greater risk, making this incorrect.

Choice C reason: Blood pressure of 100/60 mm Hg is low, but beta agonists primarily affect heart rate. A pre-existing tachycardia is more concerning contraindication, so this is incorrect.

Choice D reason: A heart rate of 120 beats/min is concerning, as beta agonists increase heart rate, risking arrhythmias. This requires evaluation before administration, making it the correct concern.

A. It directly activates receptors to affect a specific physiologic process. B. It prevents receptor activation to affect a specific physiologic process. C. It directly activates receptors to affect many physiologic processes. D. It prevents receptor activation to affect many physiologic processes.

Correct Answer is C

Explanation

Choice A reason: Nonselective agonists activate multiple receptors, not specific ones, leading to widespread effects. Specific processes are targeted by selective agonists, so this is incorrect for nonselective drugs.

Choice B reason: Nonselective agonists activate, not prevent, receptors. Prevention is the role of antagonists, so this is incorrect for a nonselective agonist’s mechanism of action.

Choice C reason: Nonselective agonists activate multiple receptor types, affecting many physiologic processes (e.g., epinephrine). This broad action is their hallmark, making it the correct choice for the drug’s effect.

Choice D reason: Preventing receptor activation describes antagonists, not agonists. Nonselective agonists stimulate multiple processes, so this is incorrect for the drug’s pharmacological action.

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A nurse teaches a patient who takes daily low-dose aspirin for protection against myocardial infarction and stroke to avoid also taking which medication?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A patient is to receive a beta agonist. Before administration of this medication, which assessment finding would most concern the nurse?

Correct Answer is D

Explanation

A nurse is preparing to administer a medication and learns that it is a nonselective agonist. What does the nurse understand about this drug?

Correct Answer is C

Explanation

What are considered the ‘Big Three’ properties of an ideal drug? (Select all that apply)

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