A nurse teaches a patient who takes daily low-dose aspirin for protection against myocardial infarction and stroke to avoid also taking which medication?
Diphenhydramine [Benadryl]
Loratadine [Claritin]
Ibuprofen [Motrin]
Multivitamin
The Correct Answer is C
Choice A reason: Diphenhydramine, an antihistamine, does not significantly interact with aspirin’s antiplatelet effects. It primarily blocks histamine receptors, affecting allergies, not platelet aggregation. While it may cause drowsiness, it doesn’t increase bleeding risk or counteract aspirin’s cardiovascular benefits, making it safe to use concurrently with low-dose aspirin.
Choice B reason: Loratadine, a second-generation antihistamine, targets histamine receptors to relieve allergy symptoms. It has no known interaction with aspirin’s antiplatelet mechanism or bleeding risk. Its minimal side effect profile makes it compatible with low-dose aspirin for cardiovascular protection, so avoiding it is unnecessary in this context.
Choice C reason: Ibuprofen, an NSAID, competes with aspirin for COX-1 binding sites, reducing aspirin’s antiplatelet effect critical for preventing myocardial infarction and stroke. It also increases gastrointestinal bleeding risk when combined with aspirin, making it contraindicated for patients on low-dose aspirin therapy, thus the correct choice to avoid.
Choice D reason: Multivitamins do not interfere with aspirin’s antiplatelet action or increase bleeding risk. They provide supplemental nutrients without affecting COX-1 inhibition or platelet aggregation. There’s no pharmacological basis for avoiding multivitamins with low-dose aspirin, making this choice irrelevant for the patient’s cardiovascular regimen.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Glargine provides basal, not insulin, coverage; meal coverage. It maintains steady glucose control, so this is incorrect.
Choice B reason: Insulin glargine offers 24-hour basal glucose control, stabilizing blood sugar without peaks. This is its primary effect, making it the correct outcome.
Choice C reason: Glargine requires regular monitoring, not less frequent monitoring, to ensure control. This is incorrect for the therapeutic outcome.
Choice D reason: Glargine has no peak, unlike short-acting insulins, with effects lasting 24 hours. A 2–4 hour peak is incorrect, so incorrect.
Correct Answer is D
Explanation
Choice A reason: To calculate the volume, divide the ordered dose (8 mg) by the concentration (5 mg/mL): 8 ÷ 5 = 1.6 mL. Choice A (1.4 mL) underestimates the volume, delivering only 7 mg (1.4 × 5), which is insufficient for the prescribed dose, making it incorrect for accurate medication administration.
Choice B reason: Calculating 8 mg ÷ 5 mg/mL yields 1.6 mL. Choice B (1.8 mL) would deliver 9 mg (1.8 × 5), exceeding the ordered dose. This overdose could increase the risk of sedation or respiratory depression, as Valium (diazepam) is a benzodiazepine with potent CNS effects, making this choice incorrect.
Choice C reason: The correct volume is 8 mg ÷ 5 mg/mL = 1.6 mL. Choice C (1.2 mL) delivers only 6 mg (1.2 × 5), which is below the prescribed dose. This underdose could result in inadequate therapeutic effects, such as insufficient anxiety relief or seizure control, making it an incorrect choice.
Choice D reason: Dividing the ordered dose (8 mg) by the concentration (5 mg/mL) gives 8 ÷ 5 = 1.6 mL. This volume accurately delivers the prescribed 8 mg of Valium, ensuring therapeutic efficacy for conditions like anxiety or seizures while minimizing risks of over- or under-dosing, making it the correct choice.
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