A nurse teaches a patient who takes daily low-dose aspirin for protection against myocardial infarction and stroke to avoid also taking which medication?
Diphenhydramine [Benadryl]
Loratadine [Claritin]
Ibuprofen [Motrin]
Multivitamin
The Correct Answer is C
Choice A reason: Diphenhydramine, an antihistamine, does not significantly interact with aspirin’s antiplatelet effects. It primarily blocks histamine receptors, affecting allergies, not platelet aggregation. While it may cause drowsiness, it doesn’t increase bleeding risk or counteract aspirin’s cardiovascular benefits, making it safe to use concurrently with low-dose aspirin.
Choice B reason: Loratadine, a second-generation antihistamine, targets histamine receptors to relieve allergy symptoms. It has no known interaction with aspirin’s antiplatelet mechanism or bleeding risk. Its minimal side effect profile makes it compatible with low-dose aspirin for cardiovascular protection, so avoiding it is unnecessary in this context.
Choice C reason: Ibuprofen, an NSAID, competes with aspirin for COX-1 binding sites, reducing aspirin’s antiplatelet effect critical for preventing myocardial infarction and stroke. It also increases gastrointestinal bleeding risk when combined with aspirin, making it contraindicated for patients on low-dose aspirin therapy, thus the correct choice to avoid.
Choice D reason: Multivitamins do not interfere with aspirin’s antiplatelet action or increase bleeding risk. They provide supplemental nutrients without affecting COX-1 inhibition or platelet aggregation. There’s no pharmacological basis for avoiding multivitamins with low-dose aspirin, making this choice irrelevant for the patient’s cardiovascular regimen.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Respiratory acidosis involves low pH and high PaCO2. Normal PaCO2 (44) and low HCO3- (12) point to metabolic acidosis, not respiratory, so this incorrect.
Choice B reason: Metabolic alkalosis has high pH and HCO3-. Low pH (7.31) and low HCO3- (12) rule this out, indicating metabolic acidosis, so this is incorrect.
Choice C reason: Low pH (7.31) and low HCO3- (12) with normal PaCO2 confirm metabolic acidosis, where acid accumulation lowers pH. This matches, making it the correct choice.
Choice D reason: Respiratory alkalosis has high pH and low PaCO2. Low pH and normal PaCO2 exclude this, pointing to metabolic acidosis, so this is incorrect.
Correct Answer is C
Explanation
Choice A reason: Adrenergic neuron blockers, like guanethidine, reduce blood pressure by inhibiting norepinephrine release. They are not first-line for stage 1 hypertension (140-159/90-99 mm Hg). Their side effects, like orthostatic hypotension, make them less suitable. Lifestyle changes are preferred initially for this patient’s mild elevation and normal diagnostic tests, making this choice inappropriate.
Choice B reason: Beta blockers, like atenolol, reduce heart rate and cardiac output, lowering blood pressure. They are not first-line for stage 1 hypertension without compelling indications (e.g., heart failure). Guidelines recommend lifestyle modifications first for this patient’s blood pressure range, as they effectively reduce risk without medication side effects, making this choice less suitable.
Choice C reason: For stage 1 hypertension (140-159/90-99 mm Hg) with normal diagnostic tests, guidelines recommend lifestyle changes, such as diet, exercise, and weight loss, as first-line treatment. These reduce blood pressure by improving vascular health and reducing cardiac strain, offering a low-risk approach to manage mild hypertension effectively, making this the correct choice.
Choice D reason: ACE inhibitors, like lisinopril, block angiotensin II formation, reducing blood pressure. They are effective but not first-line for stage 1 hypertension without comorbidities. Lifestyle changes are prioritized to avoid medication side effects like cough or hyperkalemia, making this choice less appropriate for initial management in this patient.
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