What are considered the ‘Big Three’ properties of an ideal drug? (Select all that apply)
Selectivity
Safety
Effectiveness
Irreversible action
A recognizable trade name
Correct Answer : A,B,C
Choice A reason: Selectivity ensures a drug targets specific receptors, minimizing side effects. This is a key property of an ideal drug, making it a correct choice.
Choice B reason: Safety is critical, ensuring the drug causes minimal harm at therapeutic doses. This is a fundamental ideal drug property, so it is correct.
Choice C reason: Effectiveness ensures the drug achieves its intended therapeutic effect. This is essential for an ideal drug, making it a correct choice.
Choice D reason: Irreversible action is not ideal; reversible effects allow control and safety. The ‘Big Three’ focus on efficacy, safety, and selectivity, so this is incorrect.
Choice E reason: A trade name aids marketing but is not a pharmacological property. Effectiveness, safety, and selectivity are primary, so this is incorrect.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Metabolic acidosis involves low pH and HCO3-; here, pH is normal, and HCO3- is high. Elevated PaCO2 compensates for high HCO3-, so this is incorrect for the ABG values.
Choice B reason: Normal pH (7.39), high HCO3- (29), and high PaCO2 (47) indicate metabolic alkalosis fully compensated by respiratory retention of CO2. This matches the values, making it correct.
Choice C reason: Respiratory alkalosis has low PaCO2 and normal or low HCO3-. Here, PaCO2 and HCO3- are high, ruling this out, so it’s incorrect for the given ABG profile.
Choice D reason: Respiratory acidosis has high PaCO2 and low pH. Normal pH and high HCO3- suggest metabolic alkalosis, not respiratory acidosis, making this incorrect for the values.
Correct Answer is D
Explanation
Choice A reason: Nighttime awakenings more than twice weekly indicate step 2, requiring maintenance therapy. Step 1 uses albuterol as needed, so this is incorrect.
Choice B reason: Twice-daily glucocorticoids are for step 2 or higher, not step 1, where albuterol is used as needed. This is incorrect for step 1 management.
Choice C reason: LABAs are used in step 3 or higher, not step 1, where albuterol alone is sufficient as needed. This is incorrect for the asthma step.
Choice D reason: At step 1, albuterol is used as a rescue inhaler for acute asthma symptoms. This is the standard approach, making it the correct choice.
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