The nurse should monitor for which potential clinical manifestation after administering furosemide (Lasix)?

Choice A reason: Uncompensated respiratory alkalosis requires low PaCO2 (<35 mm Hg) and high pH (>7.45). Here, PaCO2 is 48 mm Hg (high) and HCO3- is 29 mEq/L (high), indicating a metabolic cause with respiratory compensation, making this choice incorrect.

Choice B reason: Partially compensated respiratory alkalosis involves low PaCO2 and high HCO3- with high pH. With PaCO2 at 48 mm Hg (high) and HCO3- at 29 mEq/L, the alkalosis is metabolic, with elevated PaCO2 as compensation, making this choice incorrect.

Choice C reason: pH 7.48 (alkalotic), PaCO2 48 mm Hg (high), and HCO3- 29 mEq/L (high) indicate metabolic alkalosis (high HCO3-), with elevated PaCO2 showing partial respiratory compensation (hypoventilation to retain CO2). This matches partially compensated metabolic alkalosis, making it the correct choice.

Choice D reason: Uncompensated metabolic alkalosis requires high pH and high HCO3- with normal PaCO2. Here, PaCO2 is 48 mm Hg (high), indicating respiratory compensation, not an uncompensated state. This makes the condition partially compensated, so this choice is less accurate than C.

Choice A reason: A transporter shell is not a pharmacological concept; drugs use transport proteins or diffusion. Membrane crossing is key, so this is incorrect for drug movement.

Choice B reason: Selectivity and effectiveness define therapeutic action, not physical movement. Drugs must cross membranes to reach targets, so this is incorrect.

Choice C reason: Drugs must cross cell membranes to move through the body, affecting absorption and distribution. This is a fundamental requirement, making it the correct choice.

Choice D reason: An electric charge may influence solubility but isn’t required for movement. Membrane permeability is essential, so this is incorrect for drug pharmacokinetics.