A nursing instructor is describing the different categories of antiretroviral agents used in treatment for HIV infection.
The instructor determines that the teaching was successful when the students identify which category as affecting an enzyme so that new viral particles cannot mature?
Protease inhibitors.
Reverse transcriptase inhibitors.
Nonnucleoside reverse transcriptase inhibitors.
Integrase inhibitors.
The Correct Answer is A
Choice A rationale:
Protease inhibitors are a category of antiretroviral drugs used in the treatment of HIV. They work by affecting an enzyme called protease, which is necessary for the maturation of new viral particles. By inhibiting protease, these drugs prevent the formation of mature, infectious HIV particles.
Choice B rationale:
Reverse transcriptase inhibitors, including both nucleoside and non-nucleoside variants, target the enzyme reverse transcriptase. This enzyme is involved in the conversion of HIV RNA into DNA, an essential step in the viral life cycle. However, it's not about preventing the maturation of new viral particles, as mentioned in the question.
Choice C rationale:
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) also inhibit the reverse transcriptase enzyme, but they do so differently than protease inhibitors. While they are vital in HIV treatment, they do not specifically target the maturation of viral particles.
Choice D rationale:
Integrase inhibitors target the enzyme integrase, which is involved in the integration of viral DNA into the host cell's DNA. This step is crucial in the HIV life cycle, but it's not related to the maturation of new viral particles.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A rationale:
Frequency of urination increasing is not typically associated with iron supplements. Iron supplements are more likely to cause constipation or darkening of stools due to increased iron content in the stool.
Choice B rationale:
Soreness of the throat is not a common side effect of iron supplements. While iron supplements can sometimes cause gastrointestinal discomfort, sore throat is not a usual manifestation.
Choice C rationale:
Itching of the throat might occur when taking iron supplements. Iron can irritate the gastrointestinal tract, and this irritation may extend to the throat, causing mild itching or discomfort.
Choice D rationale:
The color of stools becoming darker is a common side effect of iron supplements. Iron can darken stools and make them appear black, which is known as "black, tarry stools.”. This is due to the unabsorbed iron in the gastrointestinal tract.
Correct Answer is B
Explanation
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