A nursing student asks a nurse to explain the differences between amphotericin B and the azoles group of antifungal agents. Which statement by the nurse is correct?

Choice A reason: Abdominal pain and rectal bleeding are not the primary signs of a bowel obstruction. Rectal bleeding could be indicative of other gastrointestinal issues such as hemorrhoids, diverticulosis, or colorectal cancer. While abdominal pain is a symptom of bowel obstruction, rectal bleeding is not typically associated with it.

Choice B reason: The primary symptoms of bowel obstruction include abdominal distention, pain, inability to have a bowel movement, and nausea/vomiting. When a bowel obstruction occurs, the normal movement of intestinal contents is blocked, leading to a buildup of contents and gas. This results in abdominal distention and pain. The blockage also prevents the passage of stool and gas, causing constipation or inability to have a bowel movement. Nausea and vomiting are common as the digestive system tries to expel the contents that cannot pass through the obstruction.

Choice C reason: Dehydration, back pain, and fever are not the hallmark symptoms of bowel obstruction. While dehydration can occur due to vomiting and reduced intake, back pain is not commonly associated with bowel obstruction. Fever may indicate an infection or other complications but is not a primary symptom of bowel obstruction.

Choice D reason: Diarrhea and excessive thirst are not typical signs of bowel obstruction. In fact, bowel obstruction usually leads to constipation or the inability to pass stool rather than diarrhea. Excessive thirst could be a sign of dehydration but is not specific to bowel obstruction.

Choice A reason: Hyperkalemia, or elevated potassium levels in the blood, is not typically seen in patients with SIADH. SIADH is primarily characterized by water retention and the resultant dilution of electrolytes, most notably sodium. Potassium levels are not directly affected by the antidiuretic hormone (ADH) abnormalities present in SIADH, and thus hyperkalemia is not an expected finding.

Choice B reason: Hypokalemia, which refers to low potassium levels in the blood, is also not a characteristic feature of SIADH. While potassium imbalances can occur due to a variety of conditions and medications, they are not the hallmark of SIADH. The syndrome's primary effect on electrolyte balance involves sodium, not potassium.

Choice C reason: Hyponatremia, or low sodium levels in the blood, is the defining feature of SIADH. In this condition, excessive secretion of antidiuretic hormone (ADH) leads to increased water reabsorption in the kidneys. This excess water dilutes the sodium in the bloodstream, leading to hyponatremia. The resulting imbalance can cause symptoms ranging from mild (such as headache and nausea) to severe (such as seizures and altered mental status), depending on the degree of sodium depletion.

Choice D reason: Hypercalcemia, or high calcium levels in the blood, is not associated with SIADH. The condition of SIADH affects water and sodium balance due to inappropriate ADH secretion but does not typically influence calcium levels. Hypercalcemia can be seen in other conditions, such as hyperparathyroidism or malignancies, but it is not related to the pathophysiology of SIADH.