A nursing student asks a nurse to explain the differences between amphotericin B and the azoles group of antifungal agents. Which statement by the nurse is correct?

Choice A reason: Protein restriction is not a primary treatment for prerenal kidney injury. While managing protein intake can be important in chronic kidney disease to reduce the workload on the kidneys, it is not directly relevant to the acute management of prerenal kidney injury, which primarily involves restoring adequate blood flow to the kidneys.

Choice B reason: Potassium supplementation is not typically necessary for prerenal kidney injury. In fact, in many cases of kidney injury, there is a risk of hyperkalemia (elevated potassium levels) due to reduced kidney function. Therefore, potassium levels need to be monitored, but supplementation is not a standard treatment.

Choice C reason: Fluid administration to increase cardiac output is the appropriate therapy for prerenal kidney injury. Prerenal kidney injury is caused by reduced blood flow to the kidneys, often due to factors like hypovolemia (low blood volume) or heart failure. Administering fluids helps to restore adequate blood flow and perfusion to the kidneys, which can improve kidney function and resolve the prerenal injury.

Choice D reason: Fluid restriction is not appropriate for prerenal kidney injury, which is characterized by reduced blood flow to the kidneys. In cases where hypovolemia or low cardiac output is the cause, restricting fluids would worsen the condition. Instead, increasing fluid intake helps to restore adequate perfusion to the kidneys.

Choice A reason: Bronchoconstriction refers to the narrowing of the airways in the lungs due to the contraction of the surrounding smooth muscle. This condition is typically associated with asthma or allergic reactions and is not directly related to Virchow's triad, which concerns factors leading to thrombosis (formation of blood clots).

Choice B reason: Pulmonary embolus is a blockage in one of the pulmonary arteries in the lungs, usually caused by blood clots that travel to the lungs from the legs or other parts of the body (deep vein thrombosis). Virchow's triad describes the three primary factors that predispose individuals to thrombosis: hypercoagulability (increased tendency of blood to clot), stasis of blood flow, and endothelial injury (damage to the blood vessel wall). These factors contribute to the formation of blood clots, which can ultimately result in a pulmonary embolus if they dislodge and travel to the lungs.

Choice C reason: Decreased pulmonary arterial pressure is not a consequence of the factors described in Virchow's triad. In fact, a pulmonary embolus can lead to increased pulmonary arterial pressure due to the obstruction of blood flow in the pulmonary arteries, which can strain the right side of the heart and lead to complications.

Choice D reason: Alveolar collapse, also known as atelectasis, occurs when the tiny air sacs in the lungs (alveoli) deflate or fill with fluid. This condition is typically due to reasons such as airway obstruction, surfactant deficiency, or lung compression, and is not directly related to the formation of blood clots described by Virchow's triad.