A nursing student asks how nonsteroidal anti-inflammatory drugs (NSAIDs) work to suppress inflammation and reduce pain. The nurse will explain that NSAIDs
inhibit cyclooxygenase that is necessary for prostaglandin synthesis.
exert direct actions to cause relaxation of smooth muscle.
suppress prostaglandin activity by blocking tissue receptor sites.
interfere with neuronal pathways associated with prostaglandin action.
The Correct Answer is A
A) Inhibit cyclooxygenase that is necessary for prostaglandin synthesis:
NSAIDs primarily work by inhibiting the enzyme cyclooxygenase (COX), which plays a crucial role in the conversion of arachidonic acid into prostaglandins. Prostaglandins are chemicals that promote inflammation, pain, and fever in response to injury or infection. By blocking COX, NSAIDs reduce the production of prostaglandins, thereby decreasing inflammation and alleviating pain and fever.
B) Exert direct actions to cause relaxation of smooth muscle:
NSAIDs do not directly cause the relaxation of smooth muscle. While some other classes of drugs (e.g., bronchodilators) target smooth muscle relaxation, NSAIDs primarily work by reducing the production of prostaglandins, which in turn alleviates inflammation and pain. They do not have a significant effect on smooth muscle tone itself.
C) Suppress prostaglandin activity by blocking tissue receptor sites:
NSAIDs do not block the receptor sites for prostaglandins; rather, they inhibit the cyclooxygenase enzyme, which is responsible for the synthesis of prostaglandins. This reduces the overall production of prostaglandins, rather than blocking their activity at the receptor level.
D) Interfere with neuronal pathways associated with prostaglandin action:
While NSAIDs reduce prostaglandin production, they do not directly interfere with neuronal pathways associated with prostaglandin action. They act primarily by inhibiting the cyclooxygenase enzyme to reduce the synthesis of prostaglandins at the site of injury or inflammation, rather than by modulating specific neural pathways.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A) Breath sounds: Prior to administering Atrovent (Ipratropium Bromide), it is essential for the nurse to assess the child’s breath sounds. Ipratropium is an anticholinergic medication used to relieve bronchospasm in conditions like asthma or chronic obstructive pulmonary disease (COPD). By evaluating breath sounds, the nurse can assess the severity of the respiratory condition and monitor for any wheezing or crackles, which may indicate the need for further intervention or adjustment of the treatment.
B) Cardiac disorders: While some caution may be warranted in patients with cardiac disorders when using certain medications (e.g., sympathomimetics), Ipratropium Bromide is an anticholinergic agent that primarily affects the respiratory system. It is not directly contraindicated in children with cardiac disorders, so assessing for cardiac conditions is not the most critical initial assessment when administering this drug.
C) Recent injuries: Recent injuries do not specifically relate to the need for assessment prior to administering Ipratropium. This medication targets the lungs and airways, so assessing for recent injuries would not be as pertinent unless the injuries impacted the child’s ability to breathe (e.g., rib fractures, lung trauma).
D) Hypertension: Hypertension is not a primary concern when administering Ipratropium Bromide. While anticholinergic drugs should be used cautiously in certain individuals (e.g., those with glaucoma or urinary retention), hypertension is not a contraindication for this medication. It would be more critical to assess for respiratory status, particularly breath sounds, to evaluate the efficacy of the treatment.
Correct Answer is C
Explanation
A) The patella reflex ("knee jerk") activated by tapping the patella tendon: The patellar reflex is a monosynaptic spinal reflex that involves the somatic nervous system but is a reflex action rather than a voluntary motor function. The somatic nervous system governs voluntary movements, but reflex actions like the patellar reflex are involuntary responses that do not require higher brain input, though they involve somatic motor pathways.
B) Abdominal viscera the beginning of depolarization in the cardiac conduction of impulses: This process is primarily under the control of the autonomic nervous system (ANS), not the somatic nervous system. The ANS regulates involuntary processes like heart rate and digestion, while the somatic nervous system controls voluntary movements and somatic sensation.
C) The act of typing a report using a computer keyboard: Typing is a voluntary motor activity, controlled by the somatic nervous system. The somatic system is responsible for conscious, voluntary actions such as moving muscles in the arms, hands, and fingers to type. This is the most accurate example of a somatic function.
D) Withdrawing the hand after touching a hot surface: This is a reflex action known as the "withdrawal reflex," which involves the somatic nervous system. However, it is an involuntary action triggered by a sensory stimulus. While it does involve the somatic system, it is not a voluntary action like typing, and reflexes are considered part of the automatic response mechanisms.
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