How does ephedrine act on the body?
Acts directly on alpha-Adrenergic receptor sites
Stimulates the release of norepinephrine
Acts directly on Beta-Adrenergic receptor sites
Stimulates the release of Dopamine
The Correct Answer is B
A) Acts directly on alpha-adrenergic receptor sites: Ephedrine does not act exclusively or directly on alpha-adrenergic receptors. While it can have some alpha-adrenergic effects, its primary mechanism is through the release of norepinephrine, which then activates both alpha and beta receptors. Therefore, this option is not entirely accurate for describing ephedrine's mode of action.
B) Stimulates the release of norepinephrine: Ephedrine primarily works by stimulating the release of norepinephrine from nerve terminals. The released norepinephrine then acts on both alpha and beta adrenergic receptors, leading to vasoconstriction (via alpha receptors) and increased heart rate and force of contraction (via beta receptors). This dual action helps raise blood pressure and improve cardiac output, making this the most accurate description of ephedrine's mechanism of action.
C) Acts directly on beta-adrenergic receptor sites: Although ephedrine does have beta-adrenergic effects (increasing heart rate and contractility), its primary mechanism is the indirect release of norepinephrine. It does not act directly on beta-receptors to the same extent as medications like isoproterenol. Therefore, while it does have beta-receptor activity, the main action is through norepinephrine release.
D) Stimulates the release of dopamine: Ephedrine does not primarily stimulate dopamine release. Dopamine release is more associated with drugs like levodopa or certain dopaminergic agents used in conditions like Parkinson’s disease. Ephedrine primarily affects norepinephrine and, to a lesser extent, acts on dopamine receptors, but it is not primarily a dopamine-releasing agent.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A) Stop taking the medication immediately: Abruptly stopping amitriptyline without the guidance of a healthcare provider can cause withdrawal symptoms and other complications. Discontinuing this medication should only be done under medical supervision.
B) Increase fluid intake: Amitriptyline can cause anticholinergic side effects such as dry mouth and constipation. Increasing fluid intake helps manage dry mouth by stimulating salivation and helps alleviate constipation by promoting bowel regularity.
C) Request another antidepressant: While amitriptyline can cause side effects like dry mouth and constipation, switching medications should not be the first step. These side effects are often manageable with lifestyle modifications, such as increasing fluid and fiber intake, and adjustments to the treatment plan can be considered if the symptoms are severe or persistent.
D) Notify the provider: While it is important for the nurse to document and inform the provider about any significant side effects, this instruction alone does not provide immediate relief to the patient. It is more appropriate to first recommend increasing fluid intake, and then the nurse can discuss with the provider if the symptoms persist or worsen.
Correct Answer is D
Explanation
A) The blood cells will migrate to the bone marrow:
While the bone marrow is responsible for producing red blood cells, dehydration and hypertonicity of the blood would not cause the red blood cells to migrate to the bone marrow. Migration of blood cells typically refers to white blood cells moving toward sites of infection or inflammation, not a response to dehydration.
B) The red cells will precipitate out of circulation:
Red blood cells do not precipitate out of circulation due to dehydration or hypertonic conditions. Instead, dehydration causes a shift in water balance that leads to changes in the shape and function of the red blood cells. Precipitation of cells is not a physiological response in this context.
C) They will swell and eventually rupture:
In conditions of hypertonicity, where the concentration of solutes (such as sodium) in the blood is higher than normal, red blood cells actually shrink, not swell. When blood is hypertonic, water moves out of the red blood cells into the extracellular space to balance the osmotic pressure, leading to cell shrinkage. Cells only swell in hypotonic conditions, when water moves into the cell.
D) The cells will shrink and shrivel, decreasing their oxygen-carrying ability:
When the body becomes dehydrated, the blood becomes hypertonic (more concentrated), leading to a shift of water out of the red blood cells to try to balance the osmotic gradient. As a result, the red blood cells shrink and shrivel. This shrinkage can impair their ability to carry oxygen effectively, as the cells may become more rigid and less flexible, making it difficult for them to navigate through small blood vessels and perform gas exchange in the lungs and tissues.
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