A patient who has developed opioid tolerance will experience which effect?

Decreased constipation

Increased respiratory depression

Increased euphoria

Decreased analgesic effect

Answer and Explanation

The Correct Answer is D

Choice A reason: Opioid tolerance does not reduce constipation; it may persist or worsen. Tolerance primarily reduces pain relief, so this is incorrect for the effect.

Choice B reason: Respiratory depression risk may not increase with tolerance, as sensitivity to this effect also diminishes. Analgesia is most affected, so this is incorrect.

Choice C reason: Euphoria typically decreases with tolerance, not increases, as receptor sensitivity drops. Reduced analgesia is the primary effect, so this is incorrect.

Choice D reason: Opioid tolerance leads to decreased analgesic effect, requiring higher doses for pain relief. This is the hallmark of tolerance, making it the correct choice.

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Correct Answer is B

Explanation

Choice A reason: Antidotes counteract specific toxins or drugs (e.g., naloxone for opioids). Antihistamines don’t neutralize allergens but block histamine receptors to reduce allergic symptoms like itching or sneezing. They target H1 or H2 receptors, not a toxin, making this choice incorrect for describing antihistamine mechanism of action.

Choice B reason: Antihistamines are antagonists, binding to histamine receptors (H1 or H2) without activating them, preventing histamine from triggering allergic responses like vasodilation or bronchoconstriction. This competitive inhibition reduces symptoms such as itching, sneezing, or gastric acid secretion, making this the correct choice for their pharmacological action.

Choice C reason: Agonists activate receptors to produce a response. Antihistamines block histamine receptors, not activate them, preventing allergic effects. Acting as agonists would mimic histamine, worsening symptoms like swelling or itching, which is opposite to their therapeutic role, making this choice incorrect.

Choice D reason: Activators is a vague term not used in pharmacology to describe drug action. Antihistamines specifically act as receptor antagonists, not general activators. They inhibit histamine effects without stimulating other pathways, making this choice inaccurate for explaining the mechanism of antihistamines in allergy management.

A. Fully Compensated Metabolic Acidosis B. Fully Compensated Respiratory Acidosis C. Fully Compensated Respiratory Alkalosis D. Fully Compensated Metabolic Alkalosis

Correct Answer is D

Explanation

Choice A reason: Metabolic acidosis has low pH and HCO3-. Normal pH (7.41) and high HCO3- (30) suggest alkalosis, not acidosis, so this is incorrect for the ABG values.

Choice B reason: Respiratory acidosis has high PaCO2 and low pH. Normal pH and high HCO3- indicate metabolic alkalosis, not respiratory acidosis, so this is incorrect.

Choice C reason: Respiratory alkalosis has low PaCO2 and high pH. High PaCO2 (46) and HCO3- rule this out, pointing to metabolic alkalosis, so this is incorrect.

Choice D reason: Normal pH (7.41), high PaCO2 (46), and high HCO3- (30) indicate metabolic alkalosis fully compensated by respiratory CO2 retention. This is correct.

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A patient who has developed opioid tolerance will experience which effect?

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Naxlex Comprehensive Predictor Exams

A patient has allergies and takes an antihistamine. The patient wants to know how the drug works. The nurse understands that antihistamines work because they are what?

Correct Answer is B

Explanation

Name the pulmonary imbalance using the following Arterial blood Gas (ABG) values: pH 7.41, PaCO2 46, HCO3- 30

Correct Answer is D

Explanation

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