The nurse is preparing to give a drug that will prevent receptor activation. Which term would describe this drug?

Agonist

Antagonist

Potent

Selective

Answer and Explanation

The Correct Answer is B

Choice A reason: Agonists activate receptors, mimicking endogenous ligands, not preventing activation. The drug blocks receptors, so this is incorrect for the described action.

Choice B reason: Antagonists prevent receptor activation by blocking ligand binding, inhibiting effects. This matches the drug’s action, making it the correct term.

Choice C reason: Potent describes a drug’s strength, not its mechanism of preventing receptor activation. Antagonist defines the action, so this is incorrect.

Choice D reason: Selective refers to targeting specific receptors, not preventing activation. Antagonist describes the functional role, so this is incorrect.

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Correct Answer is D

Explanation

Choice A reason: NPH insulin is not mixed with insulin glargine, as glargine’s pH and formulation cause precipitation or altered pharmacokinetics when combined. NPH can be mixed with regular insulin, as they are compatible, making this choice incorrect for the patient’s reported practice.

Choice B reason: NPH and regular insulin are compatible and routinely mixed in one syringe to provide both intermediate and short-acting coverage. They don’t react chemically or lose efficacy when combined properly, making this choice incorrect, as mixing is a standard practice in diabetes management.

Choice C reason: Mixing NPH and regular insulin does not increase potency; it combines their pharmacokinetics for basal and prandial glucose control. The mixture delivers the additive effects of each insulin’s profile without enhancing overall potency, making this choice inaccurate for their combined action.

Choice D reason: Mixing NPH (intermediate-acting) and regular insulin (short-acting) is an accepted practice to manage type 1 diabetes with one injection, covering basal and prandial needs. Proper technique (drawing regular insulin first) ensures stability, making this the correct choice for the patient’s reported insulin administration.

A. Selectivity B. Safety C. Effectiveness D. Irreversible action E. A recognizable trade name

Correct Answer is ["A","B","C"]

Explanation

Choice A reason: Selectivity ensures a drug targets specific receptors, minimizing side effects. This is a key property of an ideal drug, making it a correct choice.

Choice B reason: Safety is critical, ensuring the drug causes minimal harm at therapeutic doses. This is a fundamental ideal drug property, so it is correct.

Choice C reason: Effectiveness ensures the drug achieves its intended therapeutic effect. This is essential for an ideal drug, making it a correct choice.

Choice D reason: Irreversible action is not ideal; reversible effects allow control and safety. The ‘Big Three’ focus on efficacy, safety, and selectivity, so this is incorrect.

Choice E reason: A trade name aids marketing but is not a pharmacological property. Effectiveness, safety, and selectivity are primary, so this is incorrect.

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The nurse is preparing to give a drug that will prevent receptor activation. Which term would describe this drug?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A patient with type 1 diabetes reports mixing NPH and regular insulin to allow for one injection. The nurse knows:

Correct Answer is D

Explanation

What are considered the ‘Big Three’ properties of an ideal drug? (Select all that apply)

Correct Answer is ["A","B","C"]

Explanation

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