The healthcare provider orders Benadryl 40 mg IM now. The available concentration is 25 mg/mL. How many mL will the patient receive?

0.6 mL

1.6 mL

2 mL

1 mL

Answer and Explanation

The Correct Answer is B

Choice A reason: For 40 mg at 25 mg/mL: 40 ÷ 25 = 1.6 mL. Choice A (0.6 mL) delivers 15 mg (0.6 × 25), underdosing Benadryl, which could fail to relieve allergic symptoms or sedation needs, making this choice incorrect for the prescribed dose.

Choice B reason: Calculating 40 mg ÷ 25 mg/mL = 1.6 mL accurately delivers the ordered 40 mg of Benadryl (diphenhydramine) for allergy or sedation. This ensures therapeutic efficacy without overdose, aligning with safe administration for intramuscular delivery, making this the correct choice.

Choice C reason: For 40 mg, the volume is 40 ÷ 25 = 1.6 mL. Choice C (2 mL) delivers 50 mg (2 × 25), overdosing Benadryl, risking excessive sedation or anticholinergic effects like dry mouth or confusion, making this choice incorrect and potentially unsafe.

Choice D reason: The correct volume is 1.6 mL (40 ÷ 25). Choice D (1 mL) delivers 25 mg (1 × 25), underdosing Benadryl, which may not achieve therapeutic effects for allergies or sedation, making this choice inadequate for the prescribed dose.

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Correct Answer is C

Explanation

Choice A reason: A 25-year-old man typically has mature liver and kidney function, efficiently metabolizing and excreting CNS depressants like benzodiazepines. Toxicity risk is lower compared to neonates, whose immature systems impair drug clearance, making this choice less critical for close toxicity monitoring.

Choice B reason: A 15-year-old boy has relatively mature metabolic pathways, though not fully adult-like. CNS depressants are cleared more effectively than in neonates, reducing toxicity risk. Adolescents are less vulnerable than infants to accumulation, making this choice less concerning for drug toxicity observation.

Choice C reason: A 3-week-old neonate has immature liver enzymes (e.g., CYP450) and reduced renal clearance, increasing the risk of CNS depressant toxicity (e.g., respiratory depression, sedation). Their low body mass and underdeveloped metabolism necessitate close monitoring, making this the correct choice for heightened toxicity vigilance.

Choice D reason: A 25-year-old woman, like men of the same age, typically has efficient drug metabolism and excretion. CNS depressants pose lower toxicity risk compared to neonates, whose immature systems lead to drug accumulation, making this choice less critical for close toxicity monitoring.

A. “The glucocorticoid is used as prophylaxis to prevent exacerbations.” B. “I should use the glucocorticoid as needed when symptoms flare.” C. “I will need to use the beta2-adrenergic agonist drug daily.” D. “The beta2-adrenergic agonist suppresses the synthesis of inflammatory mediators.”

Correct Answer is A

Explanation

Choice A reason: Inhaled glucocorticoids are used daily in COPD to reduce inflammation and prevent exacerbations. This shows correct understanding, making it the correct choice.

Choice B reason: Glucocorticoids are for daily maintenance, not as-needed use, which is for beta2-agonists. This misunderstanding is incorrect for the medication regimen.

Choice C reason: Beta2-agonists are used as needed for symptom relief, not daily, in stable COPD. This is incorrect, as daily use is for maintenance drugs.

Choice D reason: Beta2-agonists relax airways, not suppress inflammation; that’s the glucocorticoid’s role. This incorrect mechanism shows misunderstanding, so it’s incorrect.

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The healthcare provider orders Benadryl 40 mg IM now. The available concentration is 25 mg/mL. How many mL will the patient receive?

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Naxlex Comprehensive Predictor Exams

When administering a central nervous system depressant, the nurse should closely observe for drug toxicity in which patient?

Correct Answer is C

Explanation

A patient with stable COPD receives prescriptions for an inhaled glucocorticoid and an inhaled beta2-adrenergic agonist. Which statement by the patient indicates an understanding of this medication regimen?

Correct Answer is A

Explanation

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