The healthcare provider orders Benadryl 40 mg IM now. The available concentration is 25 mg/mL. How many mL will the patient receive?

0.6 mL

1.6 mL

2 mL

1 mL

Answer and Explanation

The Correct Answer is B

Choice A reason: For 40 mg at 25 mg/mL: 40 ÷ 25 = 1.6 mL. Choice A (0.6 mL) delivers 15 mg (0.6 × 25), underdosing Benadryl, which could fail to relieve allergic symptoms or sedation needs, making this choice incorrect for the prescribed dose.

Choice B reason: Calculating 40 mg ÷ 25 mg/mL = 1.6 mL accurately delivers the ordered 40 mg of Benadryl (diphenhydramine) for allergy or sedation. This ensures therapeutic efficacy without overdose, aligning with safe administration for intramuscular delivery, making this the correct choice.

Choice C reason: For 40 mg, the volume is 40 ÷ 25 = 1.6 mL. Choice C (2 mL) delivers 50 mg (2 × 25), overdosing Benadryl, risking excessive sedation or anticholinergic effects like dry mouth or confusion, making this choice incorrect and potentially unsafe.

Choice D reason: The correct volume is 1.6 mL (40 ÷ 25). Choice D (1 mL) delivers 25 mg (1 × 25), underdosing Benadryl, which may not achieve therapeutic effects for allergies or sedation, making this choice inadequate for the prescribed dose.

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Correct Answer is C

Explanation

Choice A reason: A 25-year-old man typically has mature liver and kidney function, efficiently metabolizing and excreting CNS depressants like benzodiazepines. Toxicity risk is lower compared to neonates, whose immature systems impair drug clearance, making this choice less critical for close toxicity monitoring.

Choice B reason: A 15-year-old boy has relatively mature metabolic pathways, though not fully adult-like. CNS depressants are cleared more effectively than in neonates, reducing toxicity risk. Adolescents are less vulnerable than infants to accumulation, making this choice less concerning for drug toxicity observation.

Choice C reason: A 3-week-old neonate has immature liver enzymes (e.g., CYP450) and reduced renal clearance, increasing the risk of CNS depressant toxicity (e.g., respiratory depression, sedation). Their low body mass and underdeveloped metabolism necessitate close monitoring, making this the correct choice for heightened toxicity vigilance.

Choice D reason: A 25-year-old woman, like men of the same age, typically has efficient drug metabolism and excretion. CNS depressants pose lower toxicity risk compared to neonates, whose immature systems lead to drug accumulation, making this choice less critical for close toxicity monitoring.

A. Gastric cancer B. Osteoporosis C. Vitamin and mineral deficiencies D. Headaches E. Medication interactions

Correct Answer is ["B","C","E"]

Explanation

Choice A reason: Long-term proton pump inhibitor (PPI) use has a weak, controversial association with gastric cancer due to hypergastrinemia, but evidence is inconclusive. In older patients, risks like osteoporosis and nutrient deficiencies are more established and immediate concerns, making this choice less consistently worrisome compared to others.

Choice B reason: PPIs reduce gastric acid, impairing calcium absorption, which increases osteoporosis risk in older patients. Chronic use is linked to decreased bone density and higher fracture risk, particularly in the elderly, due to disrupted mineral homeostasis, making this a significant and correct adverse effect to monitor.

Choice C reason: PPIs inhibit acid production, reducing absorption of vitamin B12, magnesium, and iron, leading to deficiencies in older patients. These can cause anemia, neurological issues, or hypomagnesemia, which are particularly concerning in the elderly due to comorbidities, making this a correct and critical adverse effect.

Choice D reason: Headaches are a possible PPI side effect but are less common and less severe in older patients compared to osteoporosis, nutrient deficiencies, or drug interactions. They don’t pose a significant long-term risk or require specific monitoring, making this choice incorrect for major concerns.

Choice E reason: PPIs interact with drugs like clopidogrel, reducing its efficacy by inhibiting CYP2C19, and affect absorption of drugs requiring acidic environments. In older patients with polypharmacy, these interactions increase risks of adverse outcomes, making this a significant and correct concern for PPI use.

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The healthcare provider orders Benadryl 40 mg IM now. The available concentration is 25 mg/mL. How many mL will the patient receive?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

When administering a central nervous system depressant, the nurse should closely observe for drug toxicity in which patient?

Correct Answer is C

Explanation

Which are potentially worrisome adverse effects associated with proton pump inhibitor use in older patients? (Select all that apply)

Correct Answer is ["B","C","E"]

Explanation

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