All are negative symptoms of schizophrenia except
Delusions
Avolition
Apathy
Alogia
The Correct Answer is A
A. Delusions are a positive symptom of schizophrenia, not a negative symptom. They are false, fixed beliefs that persist despite evidence to the contrary. Common types include persecutory, grandiose, and bizarre delusions. Positive symptoms result from excess dopamine activity in the mesolimbic pathway.
B. Avolition is a negative symptom characterized by a lack of motivation to initiate and sustain goal-directed activities. It leads to difficulties with personal hygiene, work, and social engagement, significantly impairing daily functioning.
C. Apathy is a negative symptom marked by a lack of interest, enthusiasm, or emotional responsiveness. Individuals with schizophrenia may show indifference to social interactions, personal achievements, or daily activities.
D. Alogia (poverty of speech) is a negative symptom where individuals speak less and provide minimal verbal responses. This reflects impaired thought processing and reduced cognitive engagement, common in schizophrenia's mesocortical dopamine pathway dysfunction.
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Related Questions
Correct Answer is C
Explanation
A. Fetal alcohol syndrome (FAS) is a leading preventable cause of intellectual disability. Prenatal alcohol exposure disrupts brain development, leading to cognitive impairment, behavioral problems, and facial abnormalities.
B. Down syndrome (trisomy 21) is a genetic disorder that causes intellectual disability, developmental delays, and characteristic physical features. It results from an extra copy of chromosome 21, affecting brain development and cognitive function.
C. Serotonin syndrome is an acute, life-threatening condition caused by excessive serotonin activity due to medication overdose or drug interactions (e.g., SSRIs, MAOIs, MDMA). Symptoms include hyperreflexia, autonomic instability, and altered mental status, but it does not cause intellectual disability.
D. Fragile X syndrome is a genetic disorder caused by a mutation in the FMR1 gene on the X chromosome. It is the most common inherited cause of intellectual disability, leading to cognitive impairments, social anxiety, and hyperactivity, often resembling autism spectrum disorder (ASD).
Correct Answer is A
Explanation
A. Clozapine (Clozaril) is a second-generation (atypical) antipsychotic known for its strong dopamine (D2) and serotonin (5-HT2A) blockade. It is primarily used for treatment-resistant schizophrenia but has a high risk of agranulocytosis, metabolic syndrome, and sedation, requiring regular blood monitoring.
B. Haloperidol (Haldol) is a first-generation (typical) antipsychotic that strongly blocks dopamine (D2) receptors, leading to a high risk of extrapyramidal symptoms (EPS) such as dystonia, tardive dyskinesia, and akathisia. It is commonly used for acute psychosis and agitation.
C. Fluphenazine (Prolixin is a first-generation antipsychotic that also strongly antagonizes D2 receptors, making it effective for chronic schizophrenia but highly associated with EPS. It is available in long-acting injectable (LAI) form for maintenance therapy.
D. Chlorpromazine (Thorazine) is a first-generation, low-potency antipsychotic with strong sedative, anticholinergic, and hypotensive effects. While it has a lower risk of EPS compared to high-potency FGAs like haloperidol, it causes more sedation, orthostatic hypotension, and weight gain due to histamine and muscarinic receptor blockade.
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