Chronic complications of diabetes include: (Select All that Apply.)

Choice A reason: This statement is partially correct but does not fully address the question about glucose readings. The Dawn Phenomenon involves an increase in blood glucose levels in the early morning due to the release of counter-regulatory hormones (like cortisol and growth hormone) that increase insulin resistance and stimulate glucose release from the liver.

Choice B reason: This statement is true but incomplete. The Dawn Phenomenon is indeed caused by the release of certain hormones, but this option does not specify the timing or the glucose readings.

Choice C reason: While the hyperglycemia associated with the Dawn Phenomenon does typically occur between 4 a.m. and 9 a.m., this option does not fully describe the nature of the glucose readings. It is more important to note that the hyperglycemia is not due to overnight hypoglycemia.

Choice D reason: This statement accurately describes the Dawn Phenomenon. It is characterized by morning hyperglycemia that is not caused by overnight hypoglycemia. Instead, it is due to the body's natural release of counter-regulatory hormones, which increase blood glucose levels during the early morning hours.

Choice A reason: Fever is not typically the first clinical manifestation in tumors of the breast, testicle, or lymph nodes. Fever is generally more associated with infections or systemic illnesses. In the context of cancer, fever might occur in later stages due to the body's response to the tumor or secondary infections.

Choice B reason: Swelling, while it can be a symptom, is not necessarily the first clinical manifestation. Swelling can occur due to a variety of reasons, including infection, trauma, or other non-cancerous conditions. In tumors, swelling may occur as the mass grows and affects surrounding tissues, but it is not the most immediate or obvious sign.

Choice C reason: Pain is also not usually the first symptom to appear in tumors of the breast, testicle, or lymph nodes. Pain often occurs later as the tumor grows and starts pressing on nerves or other structures. Early stages of tumors are often painless, which is why they can go unnoticed for some time.

Choice D reason: The first and most common clinical manifestation of tumors in these areas is a palpable mass. This means a lump or mass that can be felt through the skin. This is particularly true for breast, testicular, and lymph node cancers. Early detection often involves physical examinations to feel for any unusual lumps.