Identify substances that, when present in significant amounts in urine, may indicate a potential diabetic health issue. (Select all that apply)

A. Glomerulus:The glomerulus is the filtration site; ADH/aldosterone act downstream on tubular epithelial cells, not on glomerular filtration directly.
B. Loop of Henle: The loop establishes the medullary gradient; ADH/aldosterone have limited direct action here (ADH affects water permeability mainly in collecting ducts; aldosterone acts mainly on DCT/collecting duct).
C. Vasa recta:Vasa recta are blood vessels that help preserve the medullary gradient (countercurrent exchange) but are not the primary hormone-target epithelial segments for ADH/aldosterone.
D. DCT and collecting duct:Aldosterone acts on the distal convoluted tubule and cortical collecting duct to increase Na⁺ reabsorption (and K⁺ secretion); ADH acts on the late DCT and collecting duct to increase water reabsorption by inserting aquaporins -together they adjust water and sodium retention.

A. Calyx, nephron, collecting duct, urinary bladder, renal pelvis, ureter, urethra: Sequence is wrong -filtrate is formed in nephron, flows into collecting duct, then into calyx → renal pelvis → ureter → bladder → urethra.
B. Nephron, collecting duct, calyx, renal pelvis, ureter, urinary bladder, urethra: Urine forms in nephron → drains into collecting duct → minor/major calyces → renal pelvis → ureter → urinary bladder → urethra for elimination.
C. Nephron, renal pelvis, collecting duct, calyx, urinary bladder, urethra, ureter:Renal pelvis and calyx order is swapped relative to collecting duct; ureter/bladder order is wrong.
D. Collecting duct, nephron, renal pelvis, calyx, urinary bladder, ureter, urethra:Collecting duct follows the nephron (not precedes it); calyx and pelvis ordering is