Individuals with diabetes are having a staggering rate of macrovascular complications due to:

Choice A reason: A catheter is a flexible tube inserted into the body to allow the passage of fluids or other substances. While catheters can be used for hemodialysis, they are typically considered temporary access points and are not created by surgically attaching an artery to a vein.

Choice B reason: A peripheral intravenous line (PIV) is a catheter placed into a small peripheral vein. PIVs are commonly used for short-term access to administer medications or fluids but are not suitable for the high flow rates needed for hemodialysis and are not surgically created by joining an artery and a vein.

Choice C reason: An arteriovenous graft (AVG) involves using a synthetic tube to connect an artery and a vein. AVGs are used for patients who cannot have an AVF due to small or weak veins. While AVGs are a viable option for hemodialysis, they are not the preferred method due to higher rates of complications like infections and clotting compared to AVFs.

Choice D reason: An arteriovenous fistula (AVF) is the preferred method of vascular access for long-term hemodialysis. It is created by surgically connecting an artery to a vein, usually in the arm. This connection allows for increased blood flow through the vein, which enlarges and strengthens it, making it suitable for repeated needle insertions during dialysis sessions. AVFs are preferred because they have lower rates of complications and provide better long-term access compared to other methods.

Choice A reason: Low white blood cell (WBC) count is not related to the development of diabetes. WBCs are part of the immune system and are involved in fighting infections. Diabetes is primarily associated with issues related to insulin, either its production or the body's response to it.

Choice B reason: Lack of insulin secretion is a primary cause of type 1 diabetes. In type 1 diabetes, the body's immune system attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body cannot produce insulin, leading to high blood glucose levels. Insulin therapy is required to manage blood glucose levels in individuals with type 1 diabetes.

Choice C reason: Low red blood cell (RBC) count, or anemia, is not a cause of diabetes. RBCs are responsible for carrying oxygen throughout the body. While anemia can occur in individuals with diabetes due to various complications, it is not a direct cause of the condition.

Choice D reason: Resistance to insulin is a primary cause of type 2 diabetes. In type 2 diabetes, the body's cells become resistant to the effects of insulin, making it difficult for glucose to enter the cells. As a result, the pancreas produces more insulin to compensate, but eventually, it cannot keep up with the demand, leading to high blood glucose levels. Lifestyle changes, oral medications, and insulin therapy are often used to manage type 2 diabetes.