Insulin glargine is prescribed for a hospitalized patient who has diabetes. When will the nurse expect to administer this drug?
In the morning and at 4:00 PM
Approximately 15 to 30 minutes before each meal
After meals and at bedtime
Once daily at bedtime
The Correct Answer is D
Choice A reason: Insulin glargine is a long-acting insulin given once daily, not twice daily. Morning and 4:00 PM dosing is typical for intermediate-acting insulins, so this incorrect for glargine’s schedule.
Choice B reason: Rapid-acting insulins are given before meals, not glargine, which provides basal coverage. Glargine is dosed once daily, so this is incorrect.
Choice C reason: Post-meal or after meals and bedtime dosing does not suit glargine’s 24-hour action. It’s given once daily, typically at bedtime, so this is incorrect for the administration timing.
Choice D reason: Insulin glargine is administered once daily, often at bedtime, to provide steady basal insulin coverage for 24 hours. This aligns with its pharmacokinetics, making it the correct choice.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
Choice A reason: Morphine, an opioid, binds to mu, kappa, and delta receptors in the brain, spinal cord, and gastrointestinal tract. Mu receptors in the gut slow peristalsis, causing constipation, while central receptors relieve pain. This multi-receptor binding explains both therapeutic and side effects, making this the correct choice.
Choice B reason: Constipation from morphine occurs at therapeutic, not just toxic, doses due to mu receptor activation in the gastrointestinal tract, which reduces motility. Toxicity may worsen side effects, but constipation is a common effect at standard doses, making this choice inaccurate for explaining morphine’s mechanism.
Choice C reason: Morphine’s receptors (e.g., mu) regulate multiple processes, but the drug itself isn’t selective to multifunctional receptors. It binds broadly to opioid receptors, causing both analgesia and side effects like constipation. This choice misrepresents morphine’s non-selective binding, making it less accurate than choice A.
Choice D reason: Morphine’s effects, including analgesia and constipation, result from specific receptor binding, not coincidental processes. It activates opioid receptors in the brain for pain relief and in the gut for reduced motility. This choice incorrectly suggests constipation is unrelated to morphine’s pharmacological action, making it incorrect.
Correct Answer is ["A","B","C"]
Explanation
Choice A reason: Selectivity ensures a drug targets specific receptors, minimizing side effects. This is a key property of an ideal drug, making it a correct choice.
Choice B reason: Safety is critical, ensuring the drug causes minimal harm at therapeutic doses. This is a fundamental ideal drug property, so it is correct.
Choice C reason: Effectiveness ensures the drug achieves its intended therapeutic effect. This is essential for an ideal drug, making it a correct choice.
Choice D reason: Irreversible action is not ideal; reversible effects allow control and safety. The ‘Big Three’ focus on efficacy, safety, and selectivity, so this is incorrect.
Choice E reason: A trade name aids marketing but is not a pharmacological property. Effectiveness, safety, and selectivity are primary, so this is incorrect.
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