A patient has had blood pressures of 150/95 and 148/90 mm Hg on two separate office visits. The patient reports a blood pressure of 145/92 mm Hg taken in an ambulatory setting. The patient’s diagnostic tests are all normal. The nurse will expect this patient’s provider to order

Choice A reason: Adrenergic neuron blockers, like guanethidine, reduce blood pressure by inhibiting norepinephrine release. They are not first-line for stage 1 hypertension (140-159/90-99 mm Hg). Their side effects, like orthostatic hypotension, make them less suitable. Lifestyle changes are preferred initially for this patient’s mild elevation and normal diagnostic tests, making this choice inappropriate.

Choice B reason: Beta blockers, like atenolol, reduce heart rate and cardiac output, lowering blood pressure. They are not first-line for stage 1 hypertension without compelling indications (e.g., heart failure). Guidelines recommend lifestyle modifications first for this patient’s blood pressure range, as they effectively reduce risk without medication side effects, making this choice less suitable.

Choice C reason: For stage 1 hypertension (140-159/90-99 mm Hg) with normal diagnostic tests, guidelines recommend lifestyle changes, such as diet, exercise, and weight loss, as first-line treatment. These reduce blood pressure by improving vascular health and reducing cardiac strain, offering a low-risk approach to manage mild hypertension effectively, making this the correct choice.

Choice D reason: ACE inhibitors, like lisinopril, block angiotensin II formation, reducing blood pressure. They are effective but not first-line for stage 1 hypertension without comorbidities. Lifestyle changes are prioritized to avoid medication side effects like cough or hyperkalemia, making this choice less appropriate for initial management in this patient.