Mary Jane comes to the clinic concerned about a painless lymph node in the neck. A diagnosis of lymphoma is made. Which of the following would indicate that the lymphoma was Hodgkin lymphoma versus non-Hodgkin lymphoma?

A. Oxygen does play a role in maintaining acid-base balance indirectly, as it is required for aerobic metabolism, which produces carbon dioxide that is regulated by the body to maintain acid-base balance. However, this is not its primary role.

B. Oxygen does trigger chemoreceptors, but this is more of a secondary function to regulate breathing based on oxygen and carbon dioxide levels.

C. While oxygen has many roles, its most critical function is providing the necessary support for cellular metabolism, which is vital for energy production in cells.

D. Oxygen is essential for cellular metabolism as it is required for the process of oxidative phosphorylation in mitochondria, which produces ATP, the energy currency of cells.

A. Pleural effusion involves the accumulation of fluid in the pleural space, which typically causes a decrease or absence of breath sounds, not wheezing.

B. Emphysema is a type of chronic obstructive pulmonary disease (COPD) that leads to damage of the alveoli and air sacs, which may result in wheezing, but it is not the most direct cause of high-pitched wheezing.

C. High-pitched wheezing is often a result of airway constriction or narrowing, which occurs in conditions like asthma, bronchitis, or anaphylaxis. The sound is caused by turbulent airflow through narrowed airways.

D. Hemoptysis refers to coughing up blood and does not cause wheezing. It is a symptom that may be associated with various respiratory conditions, but it does not directly cause the wheezing sound.