Methotrexate is prescribed for a client with rheumatoid arthritis (RA) who is also taking aspirin. Which is the best explanation for the nurse to provide as to why a second medication has been added?
Methotrexate slows the disease progression while aspirin controls the symptoms.
Methotrexate helps to reduce the side effects of the aspirin therapy.
Methotrexate enhances the effectiveness of the aspirin.
Methotrexate has less harmful side effects than aspirin.
The Correct Answer is A
A. Methotrexate is commonly used in the treatment of rheumatoid arthritis (RA) to slow the progression of the disease by suppressing the immune system's response that causes inflammation. Aspirin may be used concurrently to provide symptomatic relief from pain and inflammation associated with RA.
B. While methotrexate may have side effects, its primary indication in RA treatment is to slow disease progression rather than to mitigate aspirin side effects.
C. Methotrexate and aspirin typically work through different mechanisms of action and are not typically used together to enhance each other's effectiveness.
D. Methotrexate and aspirin have different side effect profiles, but the primary reason for adding methotrexate is to slow the progression of RA rather than to replace aspirin due to side effects.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","C","D","E","F"]
Explanation
A. Obesity is a significant risk factor for gout as it can increase uric acid production and decrease its excretion.
B. Hypertension is commonly associated with gout, potentially due to shared risk factors including kidney health and certain medications that can raise uric acid levels.
C. Alcohol, especially beer, is a well-known trigger for gout attacks because it increases uric acid production and reduces its excretion.
D. Low doses of aspirin can increase uric acid levels by reducing its excretion through the kidneys.
E. While not a direct risk factor, type 2 diabetes is often associated with metabolic syndrome, which includes several risk factors for gout.
F. Research suggests a link between sleep apnea and increased risk of gout, possibly through the effects of intermittent hypoxia on uric acid levels.
G. Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen are typically used to treat gout attacks and do not generally increase the risk of developing gout. They can, however, affect kidney function with prolonged use.
H. Smoking is not directly linked to gout risk; smoking cessation is generally beneficial for overall health but does not increase gout risk.
I. Osteoarthritis is a different type of joint disease and does not increase the risk of developing gout.
Correct Answer is D
Explanation
A. Acute pain related to renal calculus is important and needs to be addressed, but managing potential life-threatening conditions, like aspiration, takes precedence.
B. Nutritional deficit related to nausea is also a concern but is not as urgent as preventing aspiration.
C. Impaired renal function related to pain could be important in the long term, but it does not pose an immediate risk like aspiration does. Therefore, it is not the highest priority.
D. Risk for aspiration related to vomiting is the highest priority because it addresses the immediate potential for airway compromise, which can be life-threatening if the client aspirates vomitus. Ensuring the airway is protected and that aspiration does not occur is critical.
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