Methotrexate is prescribed for a client with rheumatoid arthritis (RA) who is also taking aspirin. Which is the best explanation for the nurse to provide as to why a second medication has been added?
Methotrexate slows the disease progression while aspirin controls the symptoms.
Methotrexate helps to reduce the side effects of the aspirin therapy.
Methotrexate enhances the effectiveness of the aspirin.
Methotrexate has less harmful side effects than aspirin.
The Correct Answer is A
A. Methotrexate is commonly used in the treatment of rheumatoid arthritis (RA) to slow the progression of the disease by suppressing the immune system's response that causes inflammation. Aspirin may be used concurrently to provide symptomatic relief from pain and inflammation associated with RA.
B. While methotrexate may have side effects, its primary indication in RA treatment is to slow disease progression rather than to mitigate aspirin side effects.
C. Methotrexate and aspirin typically work through different mechanisms of action and are not typically used together to enhance each other's effectiveness.
D. Methotrexate and aspirin have different side effect profiles, but the primary reason for adding methotrexate is to slow the progression of RA rather than to replace aspirin due to side effects.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Wearing braces on both wrists during the night can help maintain a neutral wrist position and alleviate pressure on the median nerve, reducing symptoms of carpal tunnel syndrome.

B. Notifying the healthcare provider may be necessary if symptoms worsen or if additional interventions are needed, but this is not the first-line intervention for managing symptoms at night.
C. Elevating the hands on two pillows at night may provide some relief, but it is not as effective as wearing wrist braces to maintain proper alignment and reduce pressure on the median nerve.
D. Applying cold compresses before bedtime may help reduce inflammation but is not specifically targeted at alleviating nighttime symptoms of carpal tunnel syndrome.
Correct Answer is B
Explanation
A. Having the client sign surgical and transfusion permits is important but not the priority in this situation.
B. Notifying the healthcare provider of the client's medication history, including heparin use, is crucial to ensure appropriate perioperative management and to prevent excessive bleeding during surgery.
C. Explaining the potential for bleeding to the client is important for informed consent but is not the priority in this situation.
D. Observing the heparin injection sites for signs of bruising is important but not the priority compared to notifying the healthcare provider about the client's medication history.
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