Mrs. Bone is Caucasian, weighs 128 lb, and is 5 foot 3 inches tall. Given her family history, she is a good example of the part that genetics plays in a person’s peak bone mass. She is 68 years of age and postmenopausal. What are risk factors you see with Mrs. Bone, and for what disorder? (Select all that apply)

Choice A reason: Latent phase follows seroconversion, not precedes infection. The correct sequence—exposure, infection, seroconversion, AIDS—reflects HIV progression. This option misorders the phases, making it incorrect for AIDS development.

Choice B reason: AIDS progresses through exposure (virus contact), infection (HIV enters body), seroconversion (antibody detection), and AIDS (advanced disease). This sequence accurately describes the disease’s history, making it correct.

Choice C reason: Symptomatic AIDS is not a distinct phase; AIDS itself is symptomatic. The standard progression includes exposure, infection, seroconversion, and AIDS, so “symptomatic AIDS” is incorrect.

Choice D reason: Window phase is part of seroconversion, not separate, and acute phase is early infection. The sequence—exposure, infection, seroconversion, AIDS—is clearer, so this is incorrect.

Choice A reason: Monitoring urine output is critical in sepsis-induced DIC, as it reflects renal perfusion and organ function. Decreased output may indicate hypoperfusion or acute kidney injury from microthrombi, common in DIC, making this a priority assessment to guide fluid and supportive therapy.

Choice B reason: White blood cell count is relevant in sepsis but less specific for DIC progression. It indicates infection severity but does not directly assess DIC’s coagulopathy or organ impact, making it a lower-priority assessment compared to organ function indicators.

Choice C reason: Level of consciousness is a priority, as DIC can cause cerebral microthrombi or hemorrhage, leading to neurological changes. Altered consciousness signals potential brain involvement or systemic hypoperfusion, necessitating immediate intervention, making this a critical assessment in sepsis with DIC.

Choice D reason: Weight assessment is not a priority in acute sepsis with DIC, as it does not directly reflect coagulopathy or organ dysfunction. Fluid shifts may occur, but urine output and other vital signs are more immediate indicators, making this non-essential.

Choice E reason: Oxygen saturation is crucial, as DIC can impair pulmonary perfusion through microthrombi, causing hypoxemia. Sepsis also increases oxygen demand, and low saturation indicates respiratory compromise, making this a priority assessment to ensure adequate oxygenation.